A new route for chitosan immobilization onto polyethylene surface

被引:46
|
作者
Popelka, Anton [1 ]
Novak, Igor [1 ]
Lehocky, Marian [2 ]
Junkar, Ita [3 ]
Mozetic, Miran [3 ]
Kleinova, Angela [1 ]
Janigova, Ivica [1 ]
Slouf, Miroslav [4 ]
Bilek, Frantisek [2 ]
Chodak, Ivan [1 ]
机构
[1] Slovak Acad Sci, Inst Polymer, Bratislava 84236, Slovakia
[2] Tomas Bata Univ Zlin, Univ Inst, Ctr Polymer Syst, Zlin 76001, Czech Republic
[3] Jozef Stefan Inst, Dept Surface Engn, Plasma Lab, SI-1000 Ljubljana, Slovenia
[4] Acad Sci Czech Republ, Inst Macromol Chem, CR-16206 Prague 6, Czech Republic
关键词
Immobilization; Plasma treatment; Chitosan; Pectin; Multilayer; Grafting; MEDICAL-GRADE PVC; DENSITY; DISCHARGE; POLYPROPYLENE; POLYMERS; ADHESION; LDPE;
D O I
10.1016/j.carbpol.2012.07.021
中图分类号
O69 [应用化学];
学科分类号
081704 ;
摘要
Low-density polyethylene (LOPE) belongs to commodity polymer materials applied in biomedical applications due to its favorable mechanical and chemical properties. The main disadvantage of LDPE in biomedical applications is low resistance to bacterial infections. An antibacterial modification of LDPE appears to be a solution to this problem. In this paper, the chitosan and chitosan/pectin multilayer was immobilized via polyacrylic acid (PAA) brushes grafted on the LDPE surface. The grafting was initiated by a low-temperature plasma treatment of the LOPE surface. Surface and adhesive properties of the samples prepared were investigated by surface analysis techniques. An antibacterial effect was confirmed by inhibition zone measurements of Escherichia colt (E. coli) and Staphylococcus aureus (S. aureus). The chitosan treatment of LDPE led to the highest and most clear inhibition zones (35 mm(2) for E. coli and 275 mm(2) for S. aureus). (C) 2012 Elsevier Ltd. All rights reserved.
引用
收藏
页码:1501 / 1508
页数:8
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