Comparative overview of emerging RNA viruses: Epidemiology, pathogenesis, diagnosis and current treatment

被引：14

作者：

Chakrabartty, Ishani ^{[1
]}

Khan, Maryam ^{[2
]}

Mahanta, Saurov ^{[3
]}

Chopra, Hitesh ^{[4
]}

Dhawan, Manish ^{[5
,6
]}

Choudhary, Om Prakash ^{[7
]}

Bibi, Shabana ^{[8
,9
]}

Mohanta, Yugal Kishore ^{[1
]}

Bin Emran, Talha ^{[10
,11
]}

机构：

[1] Univ Sci & Technol Meghalaya USTM, Sch Biol Sci, Dept Appl Biol, 9th Mile, Ri Bhoi 793101, Meghalaya, India

[2] Aligarh Muslim Univ, Fac Life Sci, Dept Biochem, Aligarh 202002, Uttar Pradesh, India

[3] Natl Inst Elect & Informat Technol NIELIT, Guwahati Ctr Guwahati, Gauhati 781008, Assam, India

[4] Chitkara Univ, Chitkara Coll Pharm, Rajpura, Punjab, India

[5] Punjab Agr Univ, Dept Microbiol, Ludhiana 141004, Punjab, India

[6] Trafford Coll, Manchester WA14 5PQ, Lancs, England

[7] Cent Agr Univ I, Coll Vet Sci & Anim Husb, Dept Vet Anat & Histol, Selesih, Aizawl, India

[8] Shifa Tameer E Millat Univ, Dept Biosci, Islamabad, Pakistan

[9] Yunnan Univ, Coll Ecol & Environm Sci, Yunnan Herbal Lab, Kunming 650091, Yunnan, Peoples R China

[10] BGC Trust Univ Bangladesh, Dept Pharm, Chittagong 4381, Bangladesh

[11] Daffodil Int Univ, Fac Allied Hlth Sci, Dept Pharm, Dhaka 1207, Bangladesh

来源：

ANNALS OF MEDICINE AND SURGERY | 2022年 / 79卷

基金：

英国科研创新办公室;

关键词：

RNA virus; COVID-19; SARS; MERS; Emerging diseases; RESPIRATORY SYNDROME CORONAVIRUS; ZIKA VIRUS; EBOLA-VIRUS; MAIN PROTEASE; SARS; INFECTION; MERS; OUTBREAK; TRANSMISSION; RISK;

D O I：

10.1016/j.amsu.2022.103985

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

From many decades, emerging infections have threatened humanity. The pandemics caused by different CoVs have already claimed and will continue to claim millions of lives. The SARS, Ebola, MERS epidemics and the most recent emergence of COVID-19 pandemic have threatened populations across borders. Since a highly pathogenic CoV has been evolved into the human population in the twenty-first century known as SARS, scientific advancements and innovative methods to tackle these viruses have increased in order to improve response preparedness towards the unpredictable threat posed by these rapidly emerging pathogens. Recently published review articles on SARS-CoV-2 have mainly focused on its pathogenesis, epidemiology and available treatments. However, in this review, we have done a systematic comparison of all three CoVs i.e., SARS, MERS and SARS-CoV-2 along with Ebola and Zika in terms of their epidemiology, virology, clinical features and current treatment strategies. This review focuses on important emerging RNA viruses starting from Zika, Ebola and the CoVs which include SARS, MERS and SARS-CoV-2. Each of these viruses has been elaborated on the basis of their epidemiology, virulence, transmission and treatment. However, special attention has been given to SARS-CoV-2 and the disease caused by it i.e., COVID-19 due to current havoc caused worldwide. At the end, insights into the current understanding of the lessons learned from previous epidemics to combat emerging CoVs have been described. The travel-related viral spread, the unprecedented nosocomial outbreaks and the high case-fatality rates associated with these highly transmissible and pathogenic viruses highlight the need for new prophylactic and therapeutic actions which include but are not limited to clinical indicators, contact tracing, and laboratory investigations as important factors that need to be taken into account in order to arrive at the final conclusion.

引用

页数：16