Advanced glycation end products, dementia, and diabetes

被引：36

作者：

Lovestone, Simon ^{[1
]}

Smith, Ulf ^{[2
]}

机构：

[1] Univ Oxford, Dept Psychiat, Oxford OX3 7JX, England

[2] Univ Gothenburg, Sahlgrenska Acad, S-41345 Gothenburg, Sweden

来源：

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | 2014年 / 111卷 / 13期

关键词：

ALZHEIMERS-DISEASE; METABOLIC SYNDROME; NEURODEGENERATION; PROTECTS; SIRTUINS; BRAIN; DIET; MICE;

D O I：

10.1073/pnas.1402277111

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

引用

页码：4743 / 4744

页数：2

共 21 条

[1] Sirtuins as Novel Targets for Alzheimer's Disease and Other Neurodegenerative Disorders: Experimental and Genetic Evidence [J].

Albani, Diego ;

Polito, Letizia ;

Forloni, Gianluigi .

JOURNAL OF ALZHEIMERS DISEASE, 2010, 19 (01) :11-26

[2] Metabolic syndrome: dietary interventions [J].

Aude, YW ;

Mego, P ;

Mehta, JL .

CURRENT OPINION IN CARDIOLOGY, 2004, 19 (05) :473-479

[3] Oral glycotoxins are a modifiable cause of dementia and the metabolic syndrome in mice and humans [J].

Cai, Weijing ;

Uribarri, Jaime ;

Zhu, Li ;

Chen, Xue ;

Swamy, Shobha ;

Zhao, Zhengshan ;

Grosjean, Fabrizio ;

Simonaro, Calogera ;

Kuchel, George A. ;

Schnaider-Beeri, Michal ;

Woodward, Mark ;

Striker, Gary E. ;

Vlassara, Helen .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2014, 111 (13) :4940-4945

[4] What renders TAU toxic [J].

Goetz, Juergen ;

Xia, Di ;

Leinenga, Gerhard ;

Chew, Yee Lian ;

Nicholas, Hannah R. .

FRONTIERS IN NEUROLOGY, 2013, 4

[5] Rosiglitazone Does Not Improve Cognition or Global Function when Used as Adjunctive Therapy to AChE Inhibitors in Mild-to-Moderate Alzheimer's Disease: Two Phase 3 Studies [J].

Harrington, C. ;

Sawchak, S. ;

Chiang, C. ;

Davies, J. ;

Donovan, C. ;

Saunders, A. M. ;

Irizarry, M. ;

Jeter, B. ;

Zvartau-Hind, M. ;

van Dyck, C. H. ;

Gold, M. .

CURRENT ALZHEIMER RESEARCH, 2011, 8 (05) :592-606

[6] The sirtuin SIRT6 regulates lifespan in male mice [J].

Kanfi, Yariv ;

Naiman, Shoshana ;

Amir, Gail ;

Peshti, Victoria ;

Zinman, Guy ;

Nahum, Liat ;

Bar-Joseph, Ziv ;

Cohen, Haim Y. .

NATURE, 2012, 483 (7388) :218-221

[7] Deletion of Irs2 reduces amyloid deposition and rescues behavioural deficits in APP transgenic mice [J].

Killick, Richard ;

Scales, Georgie ;

Leroy, Karelle ;

Causevic, Mirsada ;

Hooper, Claudie ;

Irvine, Elaine E. ;

Choudhury, Agharul I. ;

Drinkwater, Laura ;

Kerr, Fiona ;

Al-Qassab, Hind ;

Stephenson, John ;

Yilmaz, Zehra ;

Giese, K. Peter ;

Brion, Jean-Pierre ;

Withers, Dominic J. ;

Lovestone, Simon .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2009, 386 (01) :257-262

[8] SIRT1 deacetylase protects against neurodegeneration in models for Alzheimer's disease and amyotrophic lateral sclerosis [J].

Kim, Dohoon ;

Nguyen, Minh Dang ;

Dobbin, Matthew M. ;

Fischer, Andre ;

Sananbenesi, Farahnaz ;

Rodgers, Joseph T. ;

Delalle, Ivana ;

Baur, Joseph A. ;

Sui, Guangchao ;

Armour, Sean M. ;

Puigserver, Pere ;

Sinclair, David A. ;

Tsai, Li-Huei .

EMBO JOURNAL, 2007, 26 (13) :3169-3179

[9]

Kumar R, 2013, PLOS ONE, V8, DOI [10.1371/journal.pone.0061560, 10.1371/journal.pone.0074743]

[10] SirT1 inhibition reduces IGF-I/IRS-2/Ras/ERK1/2 signaling and protects neurons [J].

Li, Ying ;

Xu, Wei ;

McBurney, Michael W. ;

Longo, Valter D. .

CELL METABOLISM, 2008, 8 (01) :38-48

← 1 2 3 →