Use of novel oral anticoagulant agents in venous thromboembolism

被引:16
作者
Madan, Shivanshu [1 ]
Shah, Shenil [2 ]
Dale, Patrick [3 ]
Partovi, Sasan [4 ]
Parikh, Sahil A. [5 ,6 ,7 ]
机构
[1] Univ North Carolina Hosp, Dept Cardiovasc Med, Chapel Hill, NC USA
[2] Univ Wisconsin, Dept Cardiovasc Med, Madison, WI USA
[3] Univ North Carolina Hosp, Dept Internal Med, Chapel Hill, NC USA
[4] Univ Hosp Cleveland, Dept Radiol, Med Ctr, 2074 Abington Rd, Cleveland, OH 44106 USA
[5] Columbia Univ, Med Ctr, Ctr Intervent Vasc Therapy, 161 Ft Washington Ave,6th Floor, New York, NY 10032 USA
[6] Columbia Univ, Med Ctr, Div Cardiol, Dept Med, 161 Ft Washington Ave,6th Floor, New York, NY 10032 USA
[7] Columbia Univ Coll Phys & Surg, 161 Ft Washington Ave,6th Floor, New York, NY 10032 USA
关键词
Warfarin; dabigatran; apixaban; rivaroxaban; edoxaban; deep vein; thrombosis; pulmonary embolism (PE); FACTOR-XA INHIBITOR; VITAMIN-K ANTAGONIST; ATRIAL-FIBRILLATION; KNEE REPLACEMENT; DABIGATRAN ETEXILATE; COST-EFFECTIVENESS; ENOXAPARIN PLUS; IN-VITRO; RIVAROXABAN; THROMBOPROPHYLAXIS;
D O I
10.21037/cdt.2016.11.17
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
New oral anticoagulants (NOAC) serve as alternatives for patients currently using warfarin for the prevention and treatment of venous thromboembolic (VTE) disease. This article provides a brief summary of the clinical use of these drugs as well as a review of the landmark clinical trials which evaluated described their safety and efficacy. As more data becomes available, a fundamental understanding of these medications will be vital to cardiovascular practitioners managing patients with VTE.
引用
收藏
页码:570 / 581
页数:12
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