Biaryl product formation from cross-coupling in palladium-catalyzed borylation of a Boc protected aminobromoquinoline compound

被引：15

作者：

Fang, H ^{[1
]}

Yan, J ^{[1
]}

Wang, BH ^{[1
]}

机构：

[1] Georgia State Univ, Dept Chem, Atlanta, GA 30303 USA

来源：

MOLECULES | 2004年 / 9卷 / 03期

关键词：

palladium-catalyzed reaction; borylation; cross-coupling;

D O I：

10.3390/90300178

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The palladium catalyzed borylation of a Boc protected aminobromoquinoline compound with bis(pinacolato)diboron yielded a biaryl compound, resulting from cross coupling, as the major product, instead of the intended boronate, even though no strong base was used. Such results indicate that under certain conditions and with certain substrates, cross coupling can be a major problem during borylation, leading to unintended consequences.

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页码：178 / 184

页数：7

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