Cognitive Deficits in Geriatric Depression Clinical Correlates and Implications for Current and Future Treatment

被引:54
作者
Morimoto, Sarah Shizuko [1 ]
Alexopoulos, George S. [1 ]
机构
[1] Weill Cornell Med Coll, Dept Psychiat, Inst Geriatr Psychiat, White Plains, NY 10605 USA
关键词
Geriatric depression; Dementia; Cognitive dysfunction; Executive function; Remission; Cognitive remediation; LATE-LIFE DEPRESSION; WHITE-MATTER MICROSTRUCTURE; EXECUTIVE DYSFUNCTION; TREATMENT RESPONSE; ANTIDEPRESSANT TREATMENT; HIPPOCAMPAL VOLUME; ALZHEIMERS-DISEASE; ELDERLY-PATIENTS; PAROXETINE TREATMENT; AFFECTIVE-DISORDERS;
D O I
10.1016/j.psc.2013.08.002
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
The purpose of this article is to identify the cognitive deficits commonly associated with geriatric depression and describe their clinical significance. The complex relationship between geriatric depression and dementia is summarized and possible shared mechanisms discussed. Evidence regarding whether the cognitive deficits in depression may be mitigated with medication or with computerized cognitive remediation is presented.
引用
收藏
页码:517 / +
页数:17
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