Separation of the geometric isomers of 4-octyl-1,1a,2,3,4,5,6,6a-octahydro-cyclopropa[f]indene-1-carboxylic acid ethyl ester and their positional isomers by reversed-phase HPLC

被引：2

作者：

Hussain, Z ^{[1
]}

机构：

[1] Max Planck Inst Bioanorgan Chem, D-45470 Mulheim, Germany

来源：

CHROMATOGRAPHIA | 2006年 / 63卷 / 7-8期

关键词：

column liquid chromatography; carbene adducts; positional isomers; geometric isomers separation;

D O I：

10.1365/s10337-006-0776-z

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

A high-performance liquid chromatography (HPLC) method for the separation of geometric and positional isomers is described. A gas chromatography-mass spectrometry (GC-MS) method for the detection and evaluation of various isomers is described. The developed method was able to separate the isomers in the purity range of 97.96% to 99.3% (GC analysis).

引用

页码：327 / 330

页数：4

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