Duration of infectiousness and correlation with RT-PCR cycle threshold values in cases of COVID-19, England, January to May 2020

被引：638

作者：

Singanayagam, Anika ^{[1
]}

Patel, Monika ^{[1
]}

Charlett, Andre ^{[2
]}

Bernal, Jamie Lopez ^{[3
]}

Saliba, Vanessa ^{[3
]}

Ellis, Joanna ^{[1
]}

Ladhani, Shamez ^{[3
]}

Zambon, Maria ^{[1
]}

Gopal, Robin ^{[1
]}

机构：

[1] Publ Hlth England, Virus Reference Dept, Colindale, England

[2] Publ Hlth England, Data & Analyt Serv, Colindale, England

[3] Publ Hlth England, Immunisat & Countermeasures, Colindale, England

来源：

EUROSURVEILLANCE | 2020年 / 25卷 / 32期

关键词：

D O I：

10.2807/1560-7917.ES.2020.25.32.2001483

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Severe acute respiratory syndrome coronavirus 2 viral load in the upper respiratory tract peaks around symptom onset and infectious virus persists for 10 days in mild-to-moderate coronavirus disease (n = 324 samples analysed). RT-PCR cycle threshold (Ct) values correlate strongly with cultivable virus. Probability of culturing virus declines to 8% in samples with Ct > 35 and to 6% 10 days after onset; it is similar in asymptomatic and symptomatic persons. Asymptomatic persons represent a source of transmissible virus.

引用

页码：2 / 6

页数：5

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