High selectivity and sensitivity sensor based on MIP and SPR in tapered plastic optical fibers for the detection of L-nicotine

被引：157

作者：

Cennamo, N. ^{[1
]}

D'Agostino, G. ^{[2
]}

Pesavento, M. ^{[2
]}

Zeni, L. ^{[1
,3
]}

机构：

[1] Univ Naples 2, DIII, I-81031 Aversa, Italy

[2] Univ Pavia, Dept Chem, I-27100 Pavia, Italy

[3] CNR, IREA, I-80124 Naples, Italy

来源：

SENSORS AND ACTUATORS B-CHEMICAL | 2014年 / 191卷

关键词：

Optical biosensor; Surface plasmon resonance; Tapered plastic optical fiber; Molecularly imprinted polymers; L-Nicotine; SURFACE-PLASMON RESONANCE; MOLECULARLY IMPRINTED POLYMERS; WAVE-GUIDE; BIOSENSOR; PERFORMANCE; DESIGN;

D O I：

10.1016/j.snb.2013.10.067

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

A biomimetic sensor based on molecularly imprinted polymer (MIP) and surface plasmon resonance (SPR) transduction, in connection with tapered plastic optical fiber (POF), has been developed for the marker-free, direct and selective detection of low molecular weight substances. The device has been experimentally tested for L-nicotine ((-)-1-methyl-2-(3-pyridyl)pyrrolidine, MW = 162.24). The sensor system developed made the selective and fast detection of L-nicotine possible, with a low cost, easy to realize and small sample volume procedure. The sensor can discriminate between L- and D-nicotine. The linearity range was from 0 to 10(-3) M, and the sensitivity strongly depended on the characteristics of the tapered fiber, ranging from 1.3 x 10(4) nm/M, for a taper ratio 1.8, to 1.7 x 10(3) nm/M for a taper ratio 1, i.e. a not-tapered fiber. (C) 2013 Elsevier B.V. All rights reserved.

引用

页码：529 / 536

页数：8

共 34 条

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