Structure-based design and synthesis of aspartyl protease inhibitors

被引:0
|
作者
Ghosh, AK [1 ]
机构
[1] Univ Illinois, Dept Chem, Chicago, IL 60607 USA
关键词
D O I
暂无
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
242-MEDI
引用
收藏
页码:U2642 / U2642
页数:1
相关论文
共 50 条
  • [31] Structure-based design, synthesis and biological evaluation of β-glucuronidase inhibitors
    Khan, Khalid M.
    Ambreen, Nida
    Taha, Muhammad
    Halim, Sobia A.
    ul-Haq, Zaheer
    Naureen, Shagufta
    Rasheed, Saima
    Perveen, Shahnaz
    Ali, Sajjad
    Choudhary, Mohammad Iqbal
    JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN, 2014, 28 (05) : 577 - 585
  • [32] Structure-based design and synthesis of HIV-1 protease inhibitors employing β-D-mannopyranoside scaffolds
    Murphy, PV
    O'Brien, JL
    Gorey-Feret, LJ
    Smith, AB
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2002, 12 (13) : 1763 - 1766
  • [33] Structure-based design and synthesis of highly potent SARS-CoV 3CL protease inhibitors
    Shao, Yi-Ming
    Yang, Wen-Bin
    Peng, Hung-Pin
    Hsu, Min-Feng
    Tsa, Keng-Chang
    Kuo, Tun-Hsun
    Wang, Andrew H. -J.
    Liang, Po-Huang
    Lin, Chun-Hung
    Yang, An-Suei
    Wong, Chi-Huey
    CHEMBIOCHEM, 2007, 8 (14) : 1654 - 1657
  • [34] Structure-Based Design, Synthesis, and Evaluation of Peptide-Mimetic SARS 3CL Protease Inhibitors
    Akaji, Kenichi
    Konno, Hiroyuki
    Mitsui, Hironori
    Teruya, Kenta
    Shimamoto, Yasuhiro
    Hattori, Yasunao
    Ozaki, Takeshi
    Kusunoki, Masami
    Sanjoh, Akira
    JOURNAL OF MEDICINAL CHEMISTRY, 2011, 54 (23) : 7962 - 7973
  • [35] STRUCTURE-BASED INHIBITORS OF HIV-1 PROTEASE
    WLODAWER, A
    ERICKSON, JW
    ANNUAL REVIEW OF BIOCHEMISTRY, 1993, 62 : 543 - 585
  • [36] Structure-Based Optimization of Inhibitors of the Aspartic Protease Endothiapepsin
    Hartman, Alwin M.
    Mondal, Milon
    Radeva, Nedyalka
    Klebe, Gerhard
    Hirsch, Anna K. H.
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2015, 16 (08): : 19184 - 19194
  • [37] Nonpeptidal P-2 ligands for HIV protease inhibitors: Structure-based design, synthesis, and biological evaluation
    Ghosh, AK
    Kincaid, JF
    Walters, DE
    Chen, Y
    Chaudhuri, NC
    Thompson, WJ
    Culberson, C
    Fitzgerald, PMD
    Lee, HY
    McKee, SP
    Munson, PM
    Duong, TT
    Darke, PL
    Zugay, JA
    Schleif, WA
    Axel, MG
    Lin, J
    Huff, JR
    JOURNAL OF MEDICINAL CHEMISTRY, 1996, 39 (17) : 3278 - 3290
  • [38] Structure-based discovery of dengue virus protease inhibitors
    Tomlinson, Suzanne M.
    Malmstrom, Robert D.
    Russo, Andrew
    Mueller, Niklaus
    Pang, Yuan-Ping
    Watowich, Stanley J.
    ANTIVIRAL RESEARCH, 2009, 82 (03) : 110 - 114
  • [39] Structure-based design and synthesis of tricyclic IAP (Inhibitors of Apoptosis Proteins) inhibitors
    Hird, Alexander W.
    Aquila, Brian M.
    Block, Michael H.
    Hennessy, Edward J.
    Kamhi, Victor M.
    Omer, Charles A.
    Laing, Naomi M.
    Saeh, Jamal C.
    Sha, Li
    Yang, Bin
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2014, 24 (07) : 1820 - 1824
  • [40] Structure-based design of thrombin inhibitors
    Pfau, R
    CURRENT OPINION IN DRUG DISCOVERY & DEVELOPMENT, 2003, 6 (04) : 437 - 450