Synthesis of ferrocene-functionalized monomers for biodegradable polymer formation

被引：20

作者：

Upton, Brianna M. ^{[1
]}

Gipson, Raymond M. ^{[1
]}

Duhovic, Selma ^{[1
]}

Lydon, Brian R. ^{[1
]}

Matsumoto, Nicholas M. ^{[1
]}

Maynard, Heather D. ^{[1
]}

Diaconescu, Paula L. ^{[1
]}

机构：

[1] Univ Calif Los Angeles, Dept Chem & Biochem, Los Angeles, CA 90095 USA

来源：

INORGANIC CHEMISTRY FRONTIERS | 2014年 / 1卷 / 03期

基金：

美国国家科学基金会;

关键词：

RING-OPENING POLYMERIZATION; ALIPHATIC POLYESTERS; MEDICINAL CHEMISTRY; CYCLIC CARBONATE; CLICK CHEMISTRY; ORGANOCATALYSTS; BIOMATERIALS; EXPLORATION; RESISTANT; LACTONES;

D O I：

10.1039/c3qi00041a

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Cyclic carbonate and delta-valerolactone substrates functionalized with ferrocene were synthesized via alkyne-azide "click" cycloaddition. The cyclic carbonates were polymerized using 1,8-diazabicycloundec- 7-ene, 1-(3,5-bis(trifluoromethyl) phenyl)-3-cyclohexylthiourea, and benzyl alcohol. The resulting polymers were characterized by GPC, NMR spectroscopy, and cyclic voltammetry studies. It was found that polycarbonate molecular weights fall in the range of 4.1-5.2 x 10(3) g mol(-1) with polydispersities as low as 1.26. Electrochemistry studies allowed us to identify the monomer/polymer pair with the most desirable redox potential for biological studies.

引用

页码：271 / 277

页数：7

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