Microemulgel formulation of Kepok banana peel extract (Musa paradisiaca L) as an antioxidant

被引:0
|
作者
Sriarumtias, F. F. [1 ]
Najihudin, A. [1 ]
Putri, I. R. [1 ]
Akmal, A. [2 ]
Haindani, S. [1 ]
机构
[1] Univ Garut, Fak MIPA, Program Studi Farmasi, Jl Raya Samarang 52A, Garut, Indonesia
[2] Direktorat Kesehatan Angkatan Darat, Lembaga Farmasi, Jl Gudang Utara 26, Kota Bandung, Jawa Barat, Indonesia
关键词
EMULGEL;
D O I
10.1088/1742-6596/1402/5/055090
中图分类号
T [工业技术];
学科分类号
08 ;
摘要
The idea to utilize banana peel which had only become organic waste so far, led the researchers to conduct this study. The purpose of this study was to utilize Kepok banana peel into microemulgel which had stable characteristic and antioxidant activity. The peel of Kepok banana was extracted using maceration method with methanol solvent. The resulting extracts were then tested for antioxidant activity with the DPPH (1,1-diphenyl-2-pikrilhidrazil) method, obtained IC50 values of 659,544 ppm. Concentration extracts in microemulgel formulation were 1X IC50 (F1), 2X IC50 (F2), 3X IC50 (F3) and positive controls containing vitamin C (F4). All formulas were evaluated including organoleptic, pH, viscosity, centrifugation, dispersion, irritation test and freeze and thaw. The evaluation results showed that only formula F3 changed organoleptically and decreased viscosity. The testing of antioxidant activity microemulgel containing banana peel extract revealed that F2 was the best formula on pharmaceutical requirements with the IC50 was 638 ppm and had good stability. For all formulas after an irritation test, no erythema or udema was found. Therefore, the irritation index was zero. The benefits of this study could provide an alternative source of phytocosmetic preparations as antioxidants and utilize organic waste into something useful.
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页数:6
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