Risk factors for pulmonary tuberculosis in Russia: case-control study

被引:123
作者
Coker, R [1 ]
McKee, M
Atun, R
Dimitrova, B
Dodonova, E
Kuznetsov, S
Drobniewski, F
机构
[1] Univ London London Sch Hyg Trop Med, Dept Publ Hlth Policy, European Ctr Hlth Societies Transit, London WC1E 7HT, England
[2] Univ London Imperial Coll Sci & Technol, Tanaka Business Sch, London, England
[3] Samara Social Res Inst, Samara, Russia
[4] Samara Oblast Hlth Dept, Dept Adult Healthcare, Samara, Russia
[5] Queen Marys Sch Med, Inst Cell & Mol Sci, Mycobacterium Reference Unit, London, England
来源
BRITISH MEDICAL JOURNAL | 2006年 / 332卷 / 7533期
关键词
D O I
10.1136/bmj.38684.687940.80
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Objectives To determine risk factors for pulmonary tuberculosis in Russia. Design Case-control study of exposure to a variety of risk factors before and during the development of pulmonary tuberculosis. Setting Large city in Russia. Participants Cases were 334 consecutive adults diagnosed as having culture confirmed pulmonary tuberculosis between I January 2003 and 31 December 2003. Controls were 334 individuals sampled from a validated population registry, matched for age and sex to the patients with tuberculosis. A questionnaire collected information on potential risk factors. Main outcome measures Risk factors associated with the development of tuberculosis. Results The main risk factors for tuberculosis were low accumulated wealth (univariate odds ratio 16.70), financial insecurity (5.67), consumption of unpasteuriscd milk (3.58), diabetes (2.66), living with a relative with tuberculosis (2.94), being unemployed (6.10), living in overcrowded conditions (2.99), illicit drug use (8.74), and a history of incarceration in both pretrial detention centres (5.70) and prison (12.50). Conclusions When prevalence of exposure is taken into account the most important factors in the development of pulmonary tuberculosis in Russia are exposure to raw milk and unemployment.
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页码:85 / 87
页数:3
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