Electrochemical Nanobiosensors for Detection of Breast Cancer Biomarkers

被引：45

作者：

Gajdosova, Veronika ^{[1
]}

Lorencova, Lenka ^{[1
]}

Kasak, Peter ^{[1
]}

Tkac, Jan ^{[1
]}

机构：

[1] Qatar Univ, Ctr Adv Mat, Doha 2713, Qatar

来源：

SENSORS | 2020年 / 20卷 / 14期

关键词：

breast cancer; nanobiosensors; biomarkers; electrochemistry; impedance; immobilization; nanomaterial; nanoparticles (NPs); magnetic NPs; self-assembled monolayers (SAMs); signal amplification; SCREEN-PRINTED ELECTRODES; LABEL-FREE; CARCINOEMBRYONIC ANTIGEN; ULTRASENSITIVE DETECTION; GRAPHENE OXIDE; SENSITIVE DETECTION; SENSING PLATFORM; BIOSENSOR; NANOPARTICLES; DIAGNOSIS;

D O I：

10.3390/s20144022

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

This comprehensive review paper describes recent advances made in the field of electrochemical nanobiosensors for the detection of breast cancer (BC) biomarkers such as specific genes, microRNA, proteins, circulating tumor cells, BC cell lines, and exosomes or exosome-derived biomarkers. Besides the description of key functional characteristics of electrochemical nanobiosensors, the reader can find basic statistic information about BC incidence and mortality, breast pathology, and current clinically used BC biomarkers. The final part of the review is focused on challenges that need to be addressed in order to apply electrochemical nanobiosensors in a clinical practice.

引用

页码：1 / 37

页数：37

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