ANGIOTENSIN I CONVERTING ENZYME GENE INSERTION/DELETION POLYMORPHISM AND HUMAN PHYSICAL PERFORMANCE

被引:0
作者
Tobina, Takuro [1 ]
Tanaka, Hiroaki
Nishida, Yuichiro
Kiyonaga, Akira
机构
[1] Fukuoka Univ, Grad Sch Sports & Hlth Sci, Fukuoka, Japan
关键词
Renin-angiotensin system; Angiotensin I converting enzyme; Gene polymorphism; Physical performance;
D O I
10.7600/jspfsm.57.527
中图分类号
Q4 [生理学];
学科分类号
071003 ;
摘要
Angiotensin I converting enzyme (ACE) gene Insertion/Deletion (I/D) polymorphism was first shown as a genetic factor which influences human physical performance in 1998. Since then, various gene polymorphisms which influence physical performance and trainability have been reported. ACE is a key enzyme which produces angiotensin II in the renin-angiotensin system, and its activity was determined by I/D potymorphism. Many studies indicate that the I/I genotype is frequently found in elite eudurance athletes, while the D/D genotype is frequently found in power-oriented elite athletes. Longitudinal studies show that the D/D genotype may contribute to enhanced strength trainability. However, it is Still unclear whether the I/I genotype enhances endurance trainability. Therefore, the ACE gene I/D polymorphism can be a genetic factor which influences human physical performance.
引用
收藏
页码:527 / 531
页数:5
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