Pathogenic Escherichia coli

被引：3834

作者：

Kaper, JB ^{[1
]}

Nataro, JP

Mobley, HLT

机构：

[1] Univ Maryland, Sch Med, Ctr Vaccine Dev, Dept Microbiol & Immunol, Baltimore, MD 21201 USA

[2] Univ Maryland, Sch Med, Dept Pediat, Baltimore, MD 21201 USA

来源：

NATURE REVIEWS MICROBIOLOGY | 2004年 / 2卷 / 02期

关键词：

D O I：

10.1038/nrmicro818

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Few microorganisms are as versatile as Escherichia coli. An important member of the normal intestinal microflora of humans and other mammals, E coli has also been widely exploited as a cloning host in recombinant DNA technology. But E coli is more than just a laboratory workhorse or harmless intestinal inhabitant; it can also be a highly versatile, and frequently deadly, pathogen. Several different E coli strains cause diverse intestinal and extraintestinal diseases by means of virulence factors that affect a wide range of cellular processes.

引用

页码：123 / 140

页数：18

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