Household Transmission of Severe Acute Respiratory Syndrome Coronavirus 2 from Adults to Children

被引:29
作者
Yung, Chee Fu [1 ,2 ,3 ]
Kam, Kai-qian [1 ,2 ,4 ]
Chong, Chia Yin [1 ,2 ,3 ,4 ]
Nadua, Karen Donceras [1 ,2 ,4 ]
Li, Jiahui [1 ,2 ,4 ]
Tan, Natalie Woon Hui [1 ,2 ,3 ,4 ]
Ganapathy, Sashikumar [1 ,2 ,3 ,4 ,5 ]
Lee, Khai Pin [1 ,2 ,3 ,4 ,5 ]
Ng, Kee Chong [6 ]
Chan, Yoke Hwee [6 ]
Thoon, Koh Cheng [1 ,2 ,3 ,4 ]
机构
[1] KK Womens & Childrens Hosp, Dept Pediat, Infect Dis Serv, Singapore, Singapore
[2] Duke NUS Med Sch, Singapore, Singapore
[3] Nanyang Technol Univ, Imperial Coll London, Lee Kong Chian Sch Med, Singapore, Singapore
[4] Natl Univ Singapore, Yong Loo Lin Sch Med, Singapore, Singapore
[5] KK Womens & Childrens Hosp, Dept Pediat, Childrens Emergency, Singapore, Singapore
[6] KK Womens & Childrens Hosp, Div Med, Singapore, Singapore
关键词
COVID-19;
D O I
10.1016/j.jpeds.2020.07.009
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Knowledge of transmission dynamics of severe acute respiratory syndrome coronavirus 2 from adults to children in household settings is limited. We found an attack rate among 213 children in 137 households to be 6.1 % in house-holds with confirmed adult 2019 novel coronavirus disease index case(s). Transmission from adult to child occurred in only 5.2% of households. Young children <5 years old were at lowest risk of infection (1.3%). Children were most likely to be infected if the household index case was the mother.
引用
收藏
页码:249 / 251
页数:3
相关论文
共 13 条
[1]   Epidemiology and transmission of COVID-19 in 391 cases and 1286 of their close contacts in Shenzhen, China: a retrospective cohort study [J].
Bi, Qifang ;
Wu, Yongsheng ;
Mei, Shujiang ;
Ye, Chenfei ;
Zou, Xuan ;
Zhang, Zhen ;
Liu, Xiaojian ;
Wei, Lan ;
Truelove, Shaun A. ;
Zhang, Tong ;
Gao, Wei ;
Cheng, Cong ;
Tang, Xiujuan ;
Wu, Xiaoliang ;
Wu, Yu ;
Sun, Binbin ;
Huang, Suli ;
Sun, Yu ;
Zhang, Juncen ;
Ma, Ting ;
Lessler, Justin ;
Feng, Tiejian .
LANCET INFECTIOUS DISEASES, 2020, 20 (08) :911-919
[2]   Nasal Gene Expression of Angiotensin-Converting Enzyme 2 in Children and Adults [J].
Bunyavanich, Supinda ;
Do, Anh ;
Vicencio, Alfin .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2020, 323 (23) :2427-2429
[3]  
He Xi, 2020, Nature Medicine, V26, DOI [10.1038/s41591-020-1016-z, 10.1038/s41591-020-0869-5]
[4]  
Jing Qin-Long, 2020, medRxiv, DOI 10.1101/2020.04.11.20056010
[5]   A Well Infant With Coronavirus Disease 2019 With High Viral Load [J].
Kam, Kai-Qian ;
Yung, Chee Fu ;
Cui, Lin ;
Lin, Raymond Tzer Pin ;
Mak, Tze Minn ;
Maiwald, Matthias ;
Li, Jiahui ;
Chong, Chia Yin ;
Nadua, Karen ;
Tan, Natalie Woon Hui ;
Thoon, Koh Cheng .
CLINICAL INFECTIOUS DISEASES, 2020, 71 (15) :847-849
[6]  
Li W., 2020, Clin Infect Dis
[7]   SARS-CoV-2 Infection in Children [J].
Lu, Xiaoxia ;
Zhang, Liqiong ;
Du, Hui ;
Zhang, Jingjing ;
Li, Yuan Y. ;
Qu, Jingyu ;
Zhang, Wenxin ;
Wang, Youjie ;
Bao, Shuangshuang ;
Li, Ying ;
Wu, Chuansha ;
Liu, Hongxiu ;
Liu, Di ;
Shao, Jianbo ;
Peng, Xuehua ;
Yang, Yonghong ;
Liu, Zhisheng ;
Xiang, Yun ;
Zhang, Furong ;
Silva, Rona M. ;
Pinkerton, Kent E. ;
Shen, Kunling ;
Xiao, Han ;
Xu, Shunqing ;
Wong, Gary W. K. .
NEW ENGLAND JOURNAL OF MEDICINE, 2020, 382 (17) :1663-1665
[8]  
Luo L, MODES CONTACT RISK T, DOI [10.1101/2020.03.24.20042606., DOI 10.1101/2020.03.24.2004260]
[9]   Evaluation of the Effectiveness of Surveillance and Containment Measures for the First 100 Patients with COVID-19 in Singapore - January 2-February 29, 2020 [J].
Ng, Yixiang ;
Li, Zongbin ;
Chua, Yi Xian ;
Chaw, Wei Liang ;
Zhao, Zheng ;
Er, Benjamin ;
Pung, Rachael ;
Chiew, Calvin J. ;
Lye, David C. ;
Heng, Derrick ;
Lee, Vernon J. .
MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT, 2020, 69 (11) :307-311
[10]  
Riphagen Shelley, 2020, Lancet, V395, P1607, DOI 10.1016/S0140-6736(20)31094-1