A possible role of osteocalcin in the regulation of insulin secretion: human in vivo evidence?

被引：14
作者：
Kassi, Eva [1 ]
Papavassiliou, Athanasios G. [1 ]
机构：
[1] Univ Athens, Sch Med, Dept Biol Chem, Athens 11527, Greece
来源：
JOURNAL OF ENDOCRINOLOGY | 2008年 / 199卷 / 02期
关键词：
D O I：
10.1677/JOE-08-0294
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Recent studies have indicated a novel function for skeleton unraveling its importance in the control of energy metabolism. In the present commentary, we speculate on the meaning for bone to act as a 'rheostat' modulating glucose metabolism, and how the primitive way of communication between bone and energy metabolism through switch on/off genes (like Ptprv) evolved to a more complicated 'talking' via gain/loss of hormones activity (like osteocalcin) by carboxylation/decarboxylation process.
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收藏
页码：151 / 153
页数：3
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