Successful treatment of severe aplastic anemia with syngeneic stem cell transplantation in the setting of active disseminated mucormycosis

被引:1
作者
El-Cheikh, Jean [1 ]
Atoui, Ali [1 ]
Moukalled, Nour [1 ]
Ghaoui, Nohra [1 ]
El Darsa, Haidar [1 ]
Kanj, Souha S. [2 ]
Bazarbachi, Ali [1 ]
机构
[1] Amer Univ Beirut, Med Ctr, Dept Internal Med, Bone Marrow Transplantat Program, Beirut 1136044, Lebanon
[2] Amer Univ Beirut, Dept Internal Med, Infect Dis, Beirut, Lebanon
关键词
Mucormycosis; Severe aplastic anemia; Syngeneic transplantation; EUROPEAN GROUP; BLOOD; ASPERGILLOSIS; ZYGOMYCOSIS;
D O I
10.1016/j.mmcr.2019.01.001
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
Severe aplastic anemia (SAA) is a hematological disease resulting in pancytopenia due to bone marrow failure. Treatment consists of immunosppressive therapy, or allo-SCT. Patients with aplastic anemia are predisposed to invasive fungal infections due to mucormycosis. Till now, syngeneic SCT in the context of active mucormycosis infection for patients with severe aplastic anemia is lacking in the literature. Here, we report a case of severe aplastic anemia with disseminated mucormycosis infection undergoing syngeneic transplant.
引用
收藏
页码:68 / 71
页数:4
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