Construction of Helix-Coil Transition Curves in Heterogeneous Biopolymers Based on Melting Curves of Homopolymers

被引:0
|
作者
Andriasyan, A. K. [1 ]
机构
[1] Yerevan State Univ, Yerevan, Armenia
关键词
DNA; heteropolymers; helix-coil transition; DNA; CHAINS;
D O I
10.3103/S1068337218010127
中图分类号
O4 [物理学];
学科分类号
0702 ;
摘要
The theory of helix-coil transition in the model of the heteropolymeric DNA is considered. The theory is based on the Generalized Model of Polypeptide Chain (GMPC) with the use of the method of constrained annealing. The free energy of heteropolymers is obtained by way of the transfer-matrix of homopolymeric GMPC with the redefined parameters. The algorithm of melting curves computation based on the homopolymeric model is obtained.
引用
收藏
页码:95 / 98
页数:4
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