Association of spinal cord lesions with cognition in multiple sclerosis

被引:0
作者
Diker, Sevda [1 ]
Eker, Amber [2 ]
Kaymakamzade, Bahar [3 ]
Erem, Aysegul [4 ]
Balyemez, Ugurcan [5 ]
机构
[1] Uluslararasi Kibris Univ, Tip Fak, Norol Anabilim Dali, Lefkosa, Turkey
[2] Dogu Akdeniz Univ, Tip Fak, Norol Anabilim Dali, Famagusta, Turkey
[3] Yakindogu Univ, Tip Fak, Norol Anabilim Dali, Lefkosa, Turkey
[4] Uluslararasi Kibris Univ, Fen Edebiyat Fak, Temel Bilimier & Beseri Bilimler Bolumu, Nicosia, Turkey
[5] Yakindogu Univ, Tip Fak, Radyol Anabilim Dali, Lefkosa, Turkey
来源
CUKUROVA MEDICAL JOURNAL | 2022年 / 47卷 / 03期
关键词
Multiple sclerosis; spinal cord; cognition; BRB-N; IMPAIRMENT; DYSFUNCTION; DIAGNOSIS; ATROPHY; ABNORMALITIES; DISABILITY; OUTCOMES; VOLUME; WHITE; MRI;
D O I
10.17826/cumj.1096925
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Purpose: The effect of spinal cord involvement, which is closely related to physical disability and prognosis, on cognitive functions in multiple sclerosis. Materials and Methods: Twenty nine MS patients (2 clinically isolated syndrome, 23 relapsing and remitting MS, 2 secondary progressive MS, 2 primary progressive MS) were included in the study. Demographic characteristics, expanded disability status scale (EDSS) score, cognition assessed by brief repeatable battery of neuropsychological tests, brain and spinal cord T2 lesion number were evaluated. Results: Older age, later age of disease onset, education duration are the features affecting cognitive test results. Brain and spinal cord lesion numbers did not have any effect on cognitive tests. Patients with spinal cord lesions had higher EDSS compared to patients without, however there was no difference regarding cognitive test results between groups. Conclusion: Spinal cord lesions are associated with physical disability quantified by EDSS. Longitudinal studies with larger samples are needed to investigate the effect of presence and number of cord lesions as well as cervical cord atrophy on cognitive test results.
引用
收藏
页码:1040 / 1049
页数:10
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