Comparison of commercial molecular assays for toxigenic Clostridium difficile detection in stools: BD GeneOhm Cdiff, XPert C. difficile and illumigene C. difficile

被引：43

作者：

Viala, Celine ^{[1
]}

Le Monnier, Alban ^{[2
]}

Maataoui, Naouale ^{[2
]}

Rousseau, Clotilde ^{[1
]}

Collignon, Anne ^{[1
]}

Poilane, Isabelle ^{[1
]}

机构：

[1] Hop Jean Verdier, AP HP, Microbiol Lab, F-93140 Bondy, France

[2] Ctr Hosp Andre Mignot, Microbiol Lab, Le Chesnay, France

来源：

JOURNAL OF MICROBIOLOGICAL METHODS | 2012年 / 90卷 / 02期

关键词：

Clostridium difficile; Diagnosis; Molecular methods; REAL-TIME PCR; DIARRHEAL STOOLS; TOXIN; INFECTION; DIAGNOSIS; CULTURE;

D O I：

10.1016/j.mimet.2012.04.017

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Three commercial molecular assays were evaluated for toxigenic Clostridium difficile detection in stools. As compared to toxigenic culture, BD GeneOhm Cdiff (BD Diagnostics), XPert C. difficile (Cepheid) and illumigene C. difficile (Meridian Bioscience) demonstrated respectively a sensitivity of 95.5%. 97.8% and 86.7% and a specificity of 97.9%. 97.9% and 100%. (C) 2012 Elsevier B.V. All rights reserved.

引用

页码：83 / 85

页数：3

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