Comparison of commercial molecular assays for toxigenic Clostridium difficile detection in stools: BD GeneOhm Cdiff, XPert C. difficile and illumigene C. difficile

被引:43
作者
Viala, Celine [1 ]
Le Monnier, Alban [2 ]
Maataoui, Naouale [2 ]
Rousseau, Clotilde [1 ]
Collignon, Anne [1 ]
Poilane, Isabelle [1 ]
机构
[1] Hop Jean Verdier, AP HP, Microbiol Lab, F-93140 Bondy, France
[2] Ctr Hosp Andre Mignot, Microbiol Lab, Le Chesnay, France
关键词
Clostridium difficile; Diagnosis; Molecular methods; REAL-TIME PCR; DIARRHEAL STOOLS; TOXIN; INFECTION; DIAGNOSIS; CULTURE;
D O I
10.1016/j.mimet.2012.04.017
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
Three commercial molecular assays were evaluated for toxigenic Clostridium difficile detection in stools. As compared to toxigenic culture, BD GeneOhm Cdiff (BD Diagnostics), XPert C. difficile (Cepheid) and illumigene C. difficile (Meridian Bioscience) demonstrated respectively a sensitivity of 95.5%. 97.8% and 86.7% and a specificity of 97.9%. 97.9% and 100%. (C) 2012 Elsevier B.V. All rights reserved.
引用
收藏
页码:83 / 85
页数:3
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