Synthesis and Antimicrobial Properties of 1,3,4-Oxadiazole Analogs Containing Dibenzosuberane Moiety

被引：5

作者：

Moger, Manjunath ^{[1
,2
]}

Satam, Vijay ^{[1
]}

Govindaraju, Darshan Raj C. ^{[3
]}

Paniraj, A. S. ^{[1
]}

Gopinath, Vadiraj S. ^{[1
]}

Hindupur, Rama Mohan ^{[1
]}

Pati, Hari N. ^{[1
]}

机构：

[1] Advinus Therapeut Ltd, Peenya Ind Area, Bangalore 560058, Karnataka, India

[2] Mangalore Univ, Dept Chem, Mangalagangothri 574199, Karnataka, India

[3] Vidya Herbs Pvt Ltd, Dept Biomed Res, Bangalore 562106, Karnataka, India

来源：

JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY | 2014年 / 25卷 / 01期

关键词：

dibenzosuberane; 1,3,4-oxadiazole; antibacterial; antifungal; ANTICONVULSANT; ANTITUMOR;

D O I：

10.5935/0103-5053.20130275

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A series of ten novel 1,3,4-oxadiazole analogs containing dibenzosuberane moiety were synthesized using linear as well as convergent synthesis approach. All the compounds were characterized by mass spectrometry, infrared (IR), H-1 and C-13 nuclear magnetic resonance (H-1 NMR and C-13 NMR) spectroscopies and elemental analysis. These compounds were evaluated for antibacterial and antifungal activities. Among ten analogs, four compounds, namely, 8a, 8d, 8e and 8j were found to be highly active antibacterial and antifungal agents.

引用

页码：104 / 111

页数：8

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