Metformin-associated lactic acidosis treated successfully by peritoneal dialysis in a resource limited setting: case report

被引：4

作者：

Elmezughi, Khaled ^{[1
]}

Ekpebegh, Chukwuma ^{[1
]}

机构：

[1] Walter Sisulu Univ, Dept Internal Med, Mthatha, South Africa

来源：

PAN AFRICAN MEDICAL JOURNAL | 2019年 / 32卷

关键词：

Lactic acidosis; metformin overdose; metformin toxicity; peritoneal dialysis; South Africa; MANAGEMENT;

D O I：

10.11604/pamj.2019.32.112.18271

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Metformin is a commonly used treatment modality in type 2 diabetes mellitus with lactic acidosis as a rare but life-threatening side effect. In this case report we highlight the importance of recognizing this uncommon side effect and the treatment options in a resource limited situation. We present a 14-year-old African girl who ingested an unknown amount of metformin intentionally after an argument with her mother. She was referred late to our institution in severe lactic acidosis. Lactic acidosis resolved with appropriate treatment including peritoneal dialysis. We conclude that in resource constrained settings, peritoneal dialysis may be used for metformin associated lactic acidosis with favourable outcome.

引用

页数：5

共 14 条

[1] Metformin-associated lactic acidosis treated with continuous renal replacement therapy [J].