RET Fusion Genes in Non-Small-Cell Lung Cancer

被引:33
作者
Chao, Bo H. [1 ,2 ,3 ]
Briesewitz, Roger [2 ,3 ]
Villalona-Calero, Miguel A. [1 ,2 ,3 ]
机构
[1] Ohio State Univ, Columbus, OH 43210 USA
[2] Arthur G James Canc Hosp, Columbus, OH USA
[3] Richard J Solove Res Inst, Columbus, OH USA
关键词
PHASE-III TRIAL; TYROSINE KINASE INHIBITOR; CHRONIC MYELOID-LEUKEMIA; NEVER-SMOKERS; DOUBLE-BLIND; IDENTIFICATION; CARCINOMA; ALK; ACTIVATION; SORAFENIB;
D O I
10.1200/JCO.2012.45.8240
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
引用
收藏
页码:4439 / 4441
页数:3
相关论文
共 38 条
[1]   RET and NTRK1 proto-oncogenes in human diseases [J].
Albert, L ;
Carniti, C ;
Miranda, C ;
Roccato, E ;
Pierotti, MA .
JOURNAL OF CELLULAR PHYSIOLOGY, 2003, 195 (02) :168-186
[2]   ROS1 Rearrangements Define a Unique Molecular Class of Lung Cancers [J].
Bergethon, Kristin ;
Shaw, Alice T. ;
Ou, Sai-Hong Ignatius ;
Katayama, Ryohei ;
Lovly, Christine M. ;
McDonald, Nerina T. ;
Massion, Pierre P. ;
Siwak-Tapp, Christina ;
Gonzalez, Adriana ;
Fang, Rong ;
Mark, Eugene J. ;
Batten, Julie M. ;
Chen, Haiquan ;
Wilner, Keith D. ;
Kwak, Eunice L. ;
Clark, Jeffrey W. ;
Carbone, David P. ;
Ji, Hongbin ;
Engelman, Jeffrey A. ;
Mino-Kenudson, Mari ;
Pao, William ;
Iafrate, A. John .
JOURNAL OF CLINICAL ONCOLOGY, 2012, 30 (08) :863-870
[3]   Sorafenib for Treatment of Renal Cell Carcinoma: Final Efficacy and Safety Results of the Phase III Treatment Approaches in Renal Cancer Global Evaluation Trial [J].
Escudier, Bernard ;
Eisen, Tim ;
Stadler, Walter M. ;
Szczylik, Cezary ;
Oudard, Stephane ;
Staehler, Michael ;
Negrier, Sylvie ;
Chevreau, Christine ;
Desai, Apurva A. ;
Rolland, Frederic ;
Demkow, Tomasz ;
Hutson, Thomas E. ;
Gore, Martin ;
Anderson, Sibyl ;
Hofilena, Gloria ;
Shan, Minghua ;
Pena, Carol ;
Lathia, Chetan ;
Bukowski, Ronald M. .
JOURNAL OF CLINICAL ONCOLOGY, 2009, 27 (20) :3312-3318
[4]   New paradigms in anticancer therapy: Targeting multiple signaling pathways with kinase inhibitors [J].
Faivre, Sandrine ;
Djelloul, Siham ;
Raymond, Eric .
SEMINARS IN ONCOLOGY, 2006, 33 (04) :407-420
[5]   PTC IS A NOVEL REARRANGED FORM OF THE RET PROTO-ONCOGENE AND IS FREQUENTLY DETECTED INVIVO IN HUMAN THYROID PAPILLARY CARCINOMAS [J].
GRIECO, M ;
SANTORO, M ;
BERLINGIERI, MT ;
MELILLO, RM ;
DONGHI, R ;
BONGARZONE, I ;
PIEROTTI, MA ;
DELLAPORTA, G ;
FUSCO, A ;
VECCHIO, G .
CELL, 1990, 60 (04) :557-563
[6]   Dasatinib induces notable hematologic and cytogenetic responses in chronic-phase chronic myeloid leukemia after failure of imatinib therapy [J].
Hochhaus, Andreas ;
Kantarjian, Hagop M. ;
Baccarani, Michele ;
Lipton, Jeffrey H. ;
Apperley, Jane F. ;
Druker, Brian J. ;
Facon, Thierry ;
Goldberg, Stuart L. ;
Cervantes, Francisco ;
Niederwieser, Dietger ;
Silver, Richard T. ;
Stone, Richard M. ;
Hughes, Timothy P. ;
Muller, Martin C. ;
Ezzeddine, Rana ;
Countouriotis, Athena M. ;
Shah, Neil P. .
BLOOD, 2007, 109 (06) :2303-2309
[7]   GDNF-induced activation of the Ret protein tyrosine kinase is mediated by GDNFR-alpha, a novel receptor for GDNF [J].
Jing, SQ ;
Wen, DZ ;
Yu, YB ;
Holst, PL ;
Luo, Y ;
Fang, M ;
Tamir, R ;
Antonio, L ;
Hu, Z ;
Cupples, R ;
Louis, JC ;
Hu, S ;
Altrock, BW ;
Fox, GM .
CELL, 1996, 85 (07) :1113-1124
[8]   A transforming KIF5B and RET gene fusion in lung adenocarcinoma revealed from whole-genome and transcriptome sequencing [J].
Ju, Young Seok ;
Lee, Won-Chul ;
Shin, Jong-Yeon ;
Lee, Seungbok ;
Bleazard, Thomas ;
Won, Jae-Kyung ;
Kim, Young Tae ;
Kim, Jong-Il ;
Kang, Jin-Hyoung ;
Seo, Jeong-Sun .
GENOME RESEARCH, 2012, 22 (03) :436-445
[9]   KIF5B-RET fusions in lung adenocarcinoma [J].
Kohno, Takashi ;
Ichikawa, Hitoshi ;
Totoki, Yasushi ;
Yasuda, Kazuki ;
Hiramoto, Masaki ;
Nammo, Takao ;
Sakamoto, Hiromi ;
Tsuta, Koji ;
Furuta, Koh ;
Shimada, Yoko ;
Iwakawa, Reika ;
Ogiwara, Hideaki ;
Oike, Takahiro ;
Enari, Masato ;
Schetter, Aaron J. ;
Okayama, Hirokazu ;
Haugen, Aage ;
Skaug, Vidar ;
Chiku, Suenori ;
Yamanaka, Itaru ;
Arai, Yasuhito ;
Watanabe, Shun-ichi ;
Sekine, Ikuo ;
Ogawa, Seishi ;
Harris, Curtis C. ;
Tsuda, Hitoshi ;
Yoshida, Teruhiko ;
Yokota, Jun ;
Shibata, Tatsuhiro .
NATURE MEDICINE, 2012, 18 (03) :375-377
[10]   Anaplastic Lymphoma Kinase Inhibition in Non-Small-Cell Lung Cancer [J].
Kwak, Eunice L. ;
Bang, Yung-Jue ;
Camidge, D. Ross ;
Shaw, Alice T. ;
Solomon, Benjamin ;
Maki, Robert G. ;
Ou, Sai-Hong I. ;
Dezube, Bruce J. ;
Jaenne, Pasi A. ;
Costa, Daniel B. ;
Varella-Garcia, Marileila ;
Kim, Woo-Ho ;
Lynch, Thomas J. ;
Fidias, Panos ;
Stubbs, Hannah ;
Engelman, Jeffrey A. ;
Sequist, Lecia V. ;
Tan, WeiWei ;
Gandhi, Leena ;
Mino-Kenudson, Mari ;
Wei, Greg C. ;
Shreeve, S. Martin ;
Ratain, Mark J. ;
Settleman, Jeffrey ;
Christensen, James G. ;
Haber, Daniel A. ;
Wilner, Keith ;
Salgia, Ravi ;
Shapiro, Geoffrey I. ;
Clark, Jeffrey W. ;
Iafrate, A. John .
NEW ENGLAND JOURNAL OF MEDICINE, 2010, 363 (18) :1693-1703