Optogenetics and the future of neuroscience

被引:122
作者
Boyden, Edward S. [1 ,2 ,3 ]
机构
[1] MIT, Media Lab, Cambridge, MA 02139 USA
[2] MIT, McGovern Inst, Dept Brain & Cognit Sci, Cambridge, MA 02139 USA
[3] MIT, McGovern Inst, Dept Biol Engn, Cambridge, MA 02139 USA
关键词
NEURONAL-ACTIVITY; CHLORIDE CHANNEL; NEURAL ACTIVITY; LIGHT; CHANNELRHODOPSIN; MICROSCOPY; EXCITATION; RESOLUTION;
D O I
10.1038/nn.4094
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Over the last 10 years, optogenetics has become widespread in neuroscience for the study of how specific cell types contribute to brain functions and brain disorder states. The full impact of optogenetics will emerge only when other toolsets mature, including neural connectivity and cell phenotyping tools and neural recording and imaging tools. The latter tools are rapidly improving, in part because optogenetics has helped galvanize broad interest in neurotechnology development.
引用
收藏
页码:1200 / 1201
页数:2
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