Quinoline: A versatile heterocyclic

被引:389
作者
Marella, Akranth [1 ]
Tanwar, Om Prakash [1 ]
Saha, Rikta [1 ]
Ali, Mohammad Rahmat [1 ]
Srivastava, Sandeep [1 ]
Akhter, Mymoona [1 ]
Shaquiquzzaman, Mohammad [1 ]
Alam, Mohammad Mumtaz [1 ]
机构
[1] Jamia Hamdard, Dept Pharmaceut Chem, Fac Pharm, New Delhi 110062, India
关键词
Quinoline; Synthesis; Biological activity; ONE-POT SYNTHESIS; BIOLOGICAL EVALUATION; ANTIMALARIAL ACTIVITY; IN-VITRO; SUBSTITUTED QUINOLINES; FRIEDLANDER SYNTHESIS; RECEPTOR ANTAGONISTS; IONIC LIQUID; DERIVATIVES; CYCLIZATION;
D O I
10.1016/j.jsps.2012.03.002
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Quinoline or 1-aza-naphthalene is a weak tertiary base. Quinoline ring has been found to possess antimalarial, anti-bacterial, antifungal, anthelmintic, cardiotonic, anticonvulsant, anti-inflammatory, and analgesic activity. Quinoline not only has a wide range of biological and pharmacological activities but there are several established protocols for the synthesis of this ring. The article aims at highlighting these very diversities of the ring. (C) 2012 King Saud University. Production and hosting by Elsevier B. V. All rights reserved.
引用
收藏
页码:1 / 12
页数:12
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