Isolation and structure elucidation of anti-tyrosinase compounds from the seeds of Crotalaria pallida

被引：8

作者：

Cheng, Zhuo-Yang ^{[1
]}

Sun, Qian ^{[1
]}

Yang, Pei-Yuan ^{[1
]}

Huang, Xiao-Xiao ^{[1
]}

Song, Shao-Jiang ^{[1
]}

机构：

[1] Shenyang Pharmaceut Univ, Sch Tradit Chinese Mat Med, Key Lab Computat Chem Based Nat Antitumor Drug Re, Shenyang 110016, Peoples R China

来源：

JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH | 2021年 / 23卷 / 08期

关键词：

Fabaceae; Crotalaria pallida; phenolic compounds; anti-tyrosinase activity; FLAVONOIDS; CYTOTOXICITY; ACID;

D O I：

10.1080/10286020.2020.1782386

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Three new compounds, crotalariapallins A-C (1-3), were isolated from the 95% EtOH extract of the seeds ofCrotalaria pallida. Their structures were established based on extensive spectroscopic methods, including HRESIMS, UV, 1D and 2D NMR. All compounds were evaluated for their inhibitory activities to tyrosinase. These compounds showed different degrees of inhibitory activities, among them, compound3exhibited the strongest inhibition activity (IC50= 0.42 mM).

引用

页码：738 / 744

页数：7

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