DNA repair: Polymerases for passing lesions

被引：25

作者：

Bridges, BA ^{[1
]}

机构：

[1] Univ Sussex, MRC, Cell Mutat Unit, Brighton BN1 9RR, E Sussex, England

来源：

CURRENT BIOLOGY | 1999年 / 9卷 / 13期

关键词：

D O I：

10.1016/S0960-9822(99)80299-1

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Replicative DNA polymerases generally cannot pass lesions in the template strand. Now there is accumulating evidence for the widespread existence of a separate class of DNA polymerases that can carry out translesion synthesis in both mutagenic and error-free ways.

引用

页码：R475 / R477

页数：3

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