Chemical constituents of Ficus odorata

被引：16

作者：

Tsai, P. -W. ^{[1
]}

De Castro-Cruz, K. A. ^{[1
]}

Shen, C. -C. ^{[2
]}

Chiou, C. -T. ^{[2
]}

Ragasa, C. Y. ^{[3
,4
]}

机构：

[1] Mapua Inst Technol, Sch Chem Engn & Chem, Manila 1002, Philippines

[2] Natl Res Inst Chinese Med, Taipei 112, Taiwan

[3] De La Salle Univ, Dept Chem, Manila 1004, Philippines

[4] De La Salle Univ, Ctr Nat Sci & Ecol Res, Manila 1004, Philippines

来源：

PHARMACEUTICAL CHEMISTRY JOURNAL | 2012年 / 46卷 / 04期

关键词：

Ficus odorata; Moreaceae; beta-sitosteryl-3 beta-glucopyranoside-6 '-O-palmitate; cytotoxicity;

D O I：

10.1007/s11094-012-0767-3

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

A dichloromethane extract of the leaves of Ficus odorata (Moreaceae family) contains l-sitosteryl3 beta-glucopyranoside-6'-O-palmitate (1), squalene (2), lutein (3), alpha-amyrin acetate (4), lupeol acetate (5), and beta-carotene (6). The structure of 1 was elucidated by extensive 1D and 2D NMR spectroscopy. Compound 1 was tested for cytotoxicity using sulforhodamine B assay against the human lung adenocarcinoma epithelial cell line (A549), human stomach adenocarcinoma cell line (AGS), human colon adenocarcinoma (HT29) and human prostate cancer cell line (PC3). It exhibited cytotoxicity against AGS cell line with 60.28% growth inhibition.

引用

页码：225 / 227

页数：3

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