Angiotensin II in Vasodilatory Shock

被引：10

作者：

Wakefield, Brett J. ^{[1
,2
]}

Busse, Laurence W. ^{[3
]}

Khanna, Ashish K. ^{[1
,4
,5
]}

机构：

[1] Cleveland Clin, Dept Gen Anesthesiol, Anesthesiol Inst, 9500 Euclid Ave, Cleveland, OH 44195 USA

[2] Washington Univ, Div Crit Care Med, Dept Anesthesiol, Sch Med, 660 South Euclid Ave,Campus Box 8054, St Louis, MO 63110 USA

[3] Emory Univ, Emory St Josephs Hosp, Div Pulm Crit Care Allergy & Sleep Med, Sch Med, 5665 Peachtree Dunwoody Rd, Atlanta, GA 30342 USA

[4] Cleveland Clin, Dept Outcomes Res, Ctr Crit Care, 9500 Euclid Ave,G58, Cleveland, OH 44195 USA

[5] Wake Forest Univ, Bowman Gray Sch Med, Dept Anesthesiol, Winston Salem, NC 27109 USA

来源：

CRITICAL CARE CLINICS | 2019年 / 35卷 / 02期

关键词：

Vasodilatory shock; Septic shock; Angiotensin II; Vasopressor; Blood pressure; MEAN ARTERIAL-PRESSURE; SEPTIC SHOCK; ARGININE-VASOPRESSIN; CLINICAL-EXPERIENCE; ALDOSTERONE SYSTEM; CONVERTING-ENZYME; RENIN; NOREPINEPHRINE; MANAGEMENT; RECEPTORS;

D O I：

10.1016/j.ccc.2018.11.003

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

The Angiotensin II for the Treatment of Vasodilatory Shock (ATHOS-3) trial demonstrated the vasopressor effects and catecholamine-sparing properties of angiotensin II. As a result, the Food and Drug Administration has approved angiotensin II for the treatment of vasodilatory shock. This review details the goals of treatment of vasodilatory shock in addition to the history, current use, and recent research regarding the use of angiotensin II. An illustrative case of the use of angiotensin II is also incorporated for understanding the clinical utility of the drug.

引用

页码：229 / +

页数：18

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