Double Versus Standard Loading Dose of Ticagrelor Onset of Antiplatelet Action in Patients With STEMI Undergoing Primary PCI

被引:42
作者
Alexopoulos, Dimitrios [1 ]
Gkizas, Vassilios [1 ]
Patsilinakos, Sotirios [2 ]
Xanthopoulou, Ioanna [1 ]
Angelidis, Christos [3 ]
Anthopoulos, Prodromos [4 ]
Makris, George [1 ]
Perperis, Angelos [1 ]
Karanikas, Stavros [2 ]
Koutsogiannis, Nikolaos [1 ]
Davlouros, Periklis [1 ]
Deftereos, Spyridon [3 ]
Chiladakis, John [1 ]
Hahalis, George [1 ]
机构
[1] Patras Univ Hosp, Dept Cardiol, Patras 26500, Greece
[2] Konstantopoulio Gen Hosp, Dept Cardiol, Athens, Greece
[3] Athens Gen Hosp G Gennimatas, Dept Cardiol, Athens, Greece
[4] Evangelismos Med Ctr, Catheterizat Lab, Athens, Greece
关键词
D O I
10.1016/j.jacc.2013.05.021
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:940 / 941
页数:2
相关论文
共 5 条
[1]   Randomized Assessment of Ticagrelor Versus Prasugrel Antiplatelet Effects in Patients with ST-Segment-Elevation Myocardial Infarction [J].
Alexopoulos, Dimitrios ;
Xanthopoulou, Ioanna ;
Gkizas, Vassilios ;
Kassimis, George ;
Theodoropoulos, Konstantinos C. ;
Makris, George ;
Koutsogiannis, Nikolaos ;
Damelou, Anastasia ;
Tsigkas, Grigorios ;
Davlouros, Periklis ;
Hahalis, George .
CIRCULATION-CARDIOVASCULAR INTERVENTIONS, 2012, 5 (06) :797-804
[2]   Pharmacokinetics, pharmacodynamics, safety and tolerability of multiple ascending doses of ticagrelor in healthy volunteers [J].
Butler, Kathleen ;
Teng, Renli .
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 2010, 70 (01) :65-77
[3]   Beyond efficacy: pharmacokinetic differences between clopidogrel, prasugrel and ticagrelor [J].
Giorgi, Mariano A. ;
Cohen Arazi, Hernan ;
Gonzalez, Claudio D. ;
Di Girolamo, Guillermo .
EXPERT OPINION ON PHARMACOTHERAPY, 2011, 12 (08) :1285-1295
[4]   Randomized Double-Blind Assessment of the ONSET and OFFSET of the Antiplatelet Effects of Ticagrelor Versus Clopidogrel in Patients With Stable Coronary Artery Disease The ONSET/OFFSET Study [J].
Gurbel, Paul A. ;
Bliden, Kevin P. ;
Butler, Kathleen ;
Tantry, Udaya S. ;
Gesheff, Tania ;
Wei, Cheryl ;
Teng, Renli ;
Antonino, Mark J. ;
Patil, Shankar B. ;
Karunakaran, Arun ;
Kereiakes, Dean J. ;
Parris, Cordel ;
Purdy, Drew ;
Wilson, Vance ;
Ledley, Gary S. ;
Storey, Robert F. .
CIRCULATION, 2009, 120 (25) :2577-U103
[5]   Inhibitory Effects of Ticagrelor Compared With Clopidogrel on Platelet Function in Patients With Acute Coronary Syndromes The PLATO (PLATelet inhibition and patient Outcomes) PLATELET Substudy [J].
Storey, Robert F. ;
Angiolillo, Dominick J. ;
Patil, Shankar B. ;
Desai, Bhaloo ;
Ecob, Rosemary ;
Husted, Steen ;
Emanuelsson, Hakan ;
Cannon, Christopher P. ;
Becker, Richard C. ;
Wallentin, Lars .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2010, 56 (18) :1456-1462