Brefeldin-A: an Antiproliferative Metabolite of the Fungus Curvularia trifolii Collected from the Veracruz Coral Reef System, Mexico

被引：0

作者：

Espinoza, Cesar ^{[1
]}

Couttolenc, Alan ^{[2
]}

Fernandez, Jose J. ^{[3
]}

Norte, Manuel ^{[3
]}

Plata, Gabriela B. ^{[3
]}

Padron, Jose M. ^{[3
]}

Shnyreva, Alla ^{[4
]}

Trigos, Angel ^{[1
,2
]}

机构：

[1] Univ Veracruzana, Lab Alta Tecnol Xalapa, Calle Med 5, Xalapa 91010, Veracruz, Mexico

[2] Univ Veracruzana, Ciencias Biomed, Ave Dr Luis Castelazo Ayala S-N, Xalapa, Veracruz, Mexico

[3] Univ La Laguna, IUBO AG, Ave Astrofis Francisco Sanchez 2, San Cristobal la Laguna 38206, Spain

[4] Moscow Lomonosov State Univ, Fac Biol, Dept Mycol & Algol, Moscow, Russia

来源：

JOURNAL OF THE MEXICAN CHEMICAL SOCIETY | 2016年 / 60卷 / 02期

关键词：

Antiproliferative activity; brefeldin-A; Curvularia trifolii; Amphimedon compressa;

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

In this paper the isolation and structure analysis of three sterols and brefeldin-A from the mycelial extract of the liquid fermentation of fungus Curvularia trifolii isolated from the marine sponge Amphimedon compressa collected from the Coral Reef System of Veracruz is reported. This is the first report on the production of brefeldin- A by the fungus C. trifolii. The results on isolation biological activity support the importance of the conservation of the Mexican ecosystems of coral reefs as a source of microorganisms with a pharmaceutical potential.

引用

页码：79 / 82

页数：4

共 29 条

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