Two-Dimensional Liquid Chromatography: A State of the Art Tutorial

被引：264
作者：
Stoll, Dwight R. [1 ]
Carr, Peter W. [2 ]
机构：
[1] Gustavus Adolphus Coll, Dept Chem, St Peter, MN 56082 USA
[2] Univ Minnesota, Dept Chem, Minneapolis, MN 55104 USA
来源：
ANALYTICAL CHEMISTRY | 2017年 / 89卷 / 01期
基金：
美国国家科学基金会;
关键词：
EFFECTIVE PEAK-CAPACITY; FLIGHT MASS-SPECTROMETRY; MULTIDIMENSIONAL CHROMATOGRAPHY; ORTHOGONAL SEPARATIONS; QUANTITATIVE-ANALYSIS; COMPLEX MATRICES; RESOLVING POWER; DIMENSIONS; ONLINE; PERFORMANCE;
D O I：
10.1021/acs.analchem.6b03506
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
In this tutorial, we discuss the motivations for doing two-dimensional liquid chromatography (2DLC) and describe the commonly used implementations of the method. We review important guiding principles for method development, discuss the state of the art in 2D-LC performance as measured by peak capacity, and describe example applications from different fields that we hope will inspire new users to adopt 2D-LC for their analytical problems.
引用
收藏
页码：519 / 531
页数：13
相关论文
共 89 条
  • [11] Likelihood of total resolution in liquid chromatography: Evaluation of one-dimensional, comprehensive two-dimensional, and selective comprehensive two-dimensional liquid chromatography
    Davis, Joe M.
    Stoll, Dwight R.
    [J]. JOURNAL OF CHROMATOGRAPHY A, 2014, 1360 : 128 - 142
  • [12] Study on the performance of different types of three-dimensional chromatographic systems
    Davydova, Ekaterina
    Schoenmakers, Peter J.
    Vivo-Truyols, Gabriel
    [J]. JOURNAL OF CHROMATOGRAPHY A, 2013, 1271 : 137 - 143
  • [13] Recent advances and trends in the liquid-chromatography-mass spectrometry analysis of flavonoids
    de Villiers, Andre
    Venter, Pieter
    Pasch, Harald
    [J]. JOURNAL OF CHROMATOGRAPHY A, 2016, 1430 : 16 - 78
  • [14] A vacuum assisted dynamic evaporation interface for two-dimensional normal phase/reverse phase liquid chromatography
    Ding, Kun
    Xu, Yuan
    Wang, Hua
    Duan, Chunfeng
    Guan, Yafeng
    [J]. JOURNAL OF CHROMATOGRAPHY A, 2010, 1217 (34) : 5477 - 5483
  • [15] Comprehensive two-dimensional normal-phase (adsorption) - Reversed-phase liquid chromatography
    Dugo, P
    Favoino, O
    Luppino, R
    Dugo, G
    Mondello, L
    [J]. ANALYTICAL CHEMISTRY, 2004, 76 (09) : 2525 - 2530
  • [16] Analysis of fatty alcohol derivatives with comprehensive two-dimensional liquid chromatography coupled with mass spectrometry
    Elsner, Victoria
    Laun, Sabrina
    Melchior, David
    Koehler, Michael
    Schmitz, Oliver J.
    [J]. JOURNAL OF CHROMATOGRAPHY A, 2012, 1268 : 22 - 28
  • [17] Francois I., 2011, COMPREHENSIVE CHROMA, P281
  • [18] Tryptic digest analysis by comprehensive reversed phase x two reversed phase liquid chromatography (RP-LC x 2RP-LC) at different pH's
    Francois, Isabelle
    Cabooter, Deirdre
    Sandra, Koen
    Lynen, Frederic
    Desmet, Gert
    Sandra, Pat
    [J]. JOURNAL OF SEPARATION SCIENCE, 2009, 32 (08) : 1137 - 1144
  • [19] Reducing Dilution and Analysis Time in Online Comprehensive Two-Dimensional Liquid Chromatography by Active Modulation
    Gargano, Andrea F. G.
    Duffin, Mike
    Navarro, Pablo
    Schoenmakers, Peter J.
    [J]. ANALYTICAL CHEMISTRY, 2016, 88 (03) : 1785 - 1793
  • [20] MAXIMUM NUMBER OF COMPONENTS RESOLVABLE BY GEL FILTRATION AND OTHER ELUTION CHROMATOGRAPHIC METHODS
    GIDDINGS, JC
    [J]. ANALYTICAL CHEMISTRY, 1967, 39 (08) : 1027 - &
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