Two-Dimensional Liquid Chromatography: A State of the Art Tutorial

被引：264
作者：
Stoll, Dwight R. [1 ]
Carr, Peter W. [2 ]
机构：
[1] Gustavus Adolphus Coll, Dept Chem, St Peter, MN 56082 USA
[2] Univ Minnesota, Dept Chem, Minneapolis, MN 55104 USA
来源：
ANALYTICAL CHEMISTRY | 2017年 / 89卷 / 01期
基金：
美国国家科学基金会;
关键词：
EFFECTIVE PEAK-CAPACITY; FLIGHT MASS-SPECTROMETRY; MULTIDIMENSIONAL CHROMATOGRAPHY; ORTHOGONAL SEPARATIONS; QUANTITATIVE-ANALYSIS; COMPLEX MATRICES; RESOLVING POWER; DIMENSIONS; ONLINE; PERFORMANCE;
D O I：
10.1021/acs.analchem.6b03506
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
In this tutorial, we discuss the motivations for doing two-dimensional liquid chromatography (2DLC) and describe the commonly used implementations of the method. We review important guiding principles for method development, discuss the state of the art in 2D-LC performance as measured by peak capacity, and describe example applications from different fields that we hope will inspire new users to adopt 2D-LC for their analytical problems.
引用
收藏
页码：519 / 531
页数：13
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