A review of imaging techniques for systems biology

被引:205
作者
Kherlopian, Armen R. [2 ]
Song, Ting [1 ]
Duan, Qi [1 ]
Neimark, Mathew A. [1 ]
Po, Ming J. [1 ]
Gohagan, John K.
Laine, Andrew F. [1 ,3 ]
机构
[1] Columbia Univ, Dept Biomed Engn, New York, NY 10027 USA
[2] Cornell Univ, Weill Med Coll, Physiol Biophys & Syst Biol Program, New York, NY 10021 USA
[3] Columbia Univ, Dept Radiol, New York, NY USA
关键词
D O I
10.1186/1752-0509-2-74
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
This paper presents a review of imaging techniques and of their utility in system biology. During the last decade systems biology has matured into a distinct field and imaging has been increasingly used to enable the interplay of experimental and theoretical biology. In this review, we describe and compare the roles of microscopy, ultrasound, CT (Computed Tomography), MRI ( Magnetic Resonance Imaging), PET (Positron Emission Tomography), and molecular probes such as quantum dots and nanoshells in systems biology. As a unified application area among these different imaging techniques, examples in cancer targeting are highlighted.
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页数:18
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