Depressive Symptoms Mediate the Effect of HIV-Related Stigmatization on Medication Adherence Among HIV-Infected Men Who Have Sex with Men

被引：28

作者：

Mitzel, Luke D. ^{[1
]}

Vanable, Peter A. ^{[1
]}

Brown, Jennifer L. ^{[2
]}

Bostwick, Rebecca A. ^{[3
]}

Sweeney, Shannon M. ^{[1
]}

Carey, Michael P. ^{[4
,5
]}

机构：

[1] Syracuse Univ, Dept Psychol, Syracuse, NY 13244 USA

[2] Texas Tech Univ, Dept Psychol Sci, Lubbock, TX 79409 USA

[3] Syracuse Univ, Lerner Ctr Publ Hlth Promot, Syracuse, NY USA

[4] Miriam Hosp, Ctr Behav & Prevent Med, Providence, RI 02906 USA

[5] Brown Univ, Providence, RI 02912 USA

来源：

AIDS AND BEHAVIOR | 2015年 / 19卷 / 08期

关键词：

Stigma; Medication adherence; Depressive symptoms; MSM; HIV; COGNITIVE-BEHAVIORAL THERAPY; RANDOMIZED CONTROLLED-TRIAL; ANTIRETROVIRAL THERAPY; CBT-AD; DRUG-USERS; STIGMA; PEOPLE; HEALTH; RISK; METAANALYSIS;

D O I：

10.1007/s10461-015-1038-6

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

This study tested the hypothesis that depressive symptoms would mediate the association of HIV-related stigma to medication adherence. We recruited HIV-infected men who have sex with men (MSM; N = 66; 66 % White, 23 % African-American) from an outpatient infectious disease clinic, and asked them to complete self-report measures. Mediational analyses showed that depressive symptoms fully mediated the association between HIV-related stigma and adherence. That is, stigma-related experiences were positively associated with depressive symptoms and negatively associated with adherence, and, in the final model, depressive symptoms remained a significant correlate of adherence while stigma did not. A test of the indirect effect of stigma on adherence through depressive symptoms was also significant (unstandardized b = -0.19; bootstrap 95 % CI -0.45 to -0.01). These results highlight the importance of treating depressive symptoms in interventions aiming to improve medication adherence among HIV-infected MSM.

引用

页码：1454 / 1459

页数：6

共 42 条

[1]

[Anonymous], 2012, HIVAIDS SURVEILLANCE, V17, P1

[2] Antiretroviral therapy adherence and viral suppression in HIV-infected drug users: Comparison of self-report and electronic monitoring [J].

Arnsten, JH ;

Demas, PA ;

Farzadegan, H ;

Grant, RW ;

Gourevitch, MN ;

Chang, CJ ;

Buono, D ;

Eckholdt, H ;

Howard, AA ;

Schoenbaum, EE .

CLINICAL INFECTIOUS DISEASES, 2001, 33 (08) :1417-1423

[3] THE MODERATOR MEDIATOR VARIABLE DISTINCTION IN SOCIAL PSYCHOLOGICAL-RESEARCH - CONCEPTUAL, STRATEGIC, AND STATISTICAL CONSIDERATIONS [J].

BARON, RM ;

KENNY, DA .

JOURNAL OF PERSONALITY AND SOCIAL PSYCHOLOGY, 1986, 51 (06) :1173-1182

[4] Changes in the risk of death after HIV seroconversion compared with mortality in the general population [J].

Bhaskaran, Krishnan ;

Hamouda, Osamah ;

Sannes, Mette ;

Boufassa, Faroudy ;

Johnson, Anne M. ;

Lambert, Paul C. ;

Porter, Kholoud .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2008, 300 (01) :51-59

[5] Patterns, correlates, and barriers to medication adherence among persons prescribed new treatments for HIV disease [J].

Catz, SL ;

Kelly, JA ;

Bogart, LM ;

Benotsch, EG ;

McAuliffe, TL .

HEALTH PSYCHOLOGY, 2000, 19 (02) :124-133

[6] Self-reported adherence to antiretroviral medications among participants in HIV clinical trials: the AACTG Adherence Instruments [J].

Chesney, MA ;

Ickovics, JR ;

Chambers, DB ;

Gifford, AL ;

Neidig, J ;

Zwickl, B ;

Wu, AW .

AIDS CARE-PSYCHOLOGICAL AND SOCIO-MEDICAL ASPECTS OF AIDS/HIV, 2000, 12 (03) :255-266

[7] Adherence to Antiretroviral Medication Regimens: A Test of a Psychosocial Model [J].

DiIorio, Colleen ;

McCarty, Frances ;

DePadilla, Lara ;

Resnicow, Ken ;

Holstad, Marcia McDonnell ;

Yeager, Katherine ;

Sharma, Sanjay M. ;

Morisky, Donald E. ;

Lundberg, Brita .

AIDS AND BEHAVIOR, 2009, 13 (01) :10-22

[8]

Dodeen H. M., 2003, Assessment and Evaluation in Higher Education, V28, P505, DOI [10.1080/02602930301674, DOI 10.1080/02602930301674]

[9] HIV Stigma Mechanisms and Well-Being Among PLWH: A Test of the HIV Stigma Framework [J].

Earnshaw, Valerie A. ;

Smith, Laramie R. ;

Chaudoir, Stephenie R. ;

Amico, K. Rivet ;

Copenhaver, Michael M. .

AIDS AND BEHAVIOR, 2013, 17 (05) :1785-1795

[10] Perceived stigma reductions following participation in mental health services integrated within community-based HIV primary care [J].

Farber, Eugene W. ;

Shahane, Amit A. ;

Brown, Jennifer L. ;

Campos, Peter E. .

AIDS CARE-PSYCHOLOGICAL AND SOCIO-MEDICAL ASPECTS OF AIDS/HIV, 2014, 26 (06) :750-753

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