A Study on Left Ventricular Mass of Patients Having Hypertension in Women with Menopause

被引:0
作者
Krishna, Daya Sindhu [1 ]
Manivel, T. [1 ]
Palaniandavan, S. [1 ]
机构
[1] Bharath Inst Higher Educ & Res, Sree Balaji Med Coll & Hosp, Dept Gen Med, Chennai, Tamil Nadu, India
关键词
Left ventricular mass; hypertension; diabetes; menopause; ESTROGEN-RECEPTOR-ALPHA; ESTRADIOL;
D O I
10.9734/JPRI/2020/v32i1430605
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Increase in left-ventricular mass has become an important risk factor for cardiovascular morbidity and mortality. Although, there is an obvious change in the cardiac size with respect to age and the hypertrophic stimuli, it is very different in men and women. In men the left ventricular mass may remain constant with age, while in women it increases with age. These findings are even more pronounced in women more than 50 years of age who have attained menopause. This study is to show that even though left ventricular mass increases in menopausal women compared to younger women in the reproductive age group, it is more severe in women who have hypertension.
引用
收藏
页码:50 / 53
页数:4
相关论文
共 8 条
[1]  
Basile Jan, 2003, J Clin Hypertens (Greenwich), V5, P353
[2]  
Brouchet L, 2001, CIRCULATION, V103, P423
[3]   Molecular and cellular basis of cardiovascular gender differences [J].
Mendelsohn, ME ;
Karas, RH .
SCIENCE, 2005, 308 (5728) :1583-1587
[4]   Estrogen receptor-α mediates the protective effects of estrogen against vascular injury [J].
Pare, G ;
Krust, A ;
Karas, RH ;
Dupont, S ;
Aronovitz, M ;
Chambon, P ;
Mendelsohn, ME .
CIRCULATION RESEARCH, 2002, 90 (10) :1087-1092
[5]   The AF-1 activation-function of ERα may be dispensable to mediate the effect of estradiol on endothelial NO production in mice [J].
Pendaries, C ;
Darblade, B ;
Rochaix, P ;
Krust, A ;
Chambon, P ;
Korach, KS ;
Bayard, F ;
Arnal, JF .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2002, 99 (04) :2205-2210
[6]   EFFECTS OF POSTMENOPAUSAL ESTROGEN REPLACEMENT ON THE CONCENTRATIONS AND METABOLISM OF PLASMA-LIPOPROTEINS [J].
WALSH, BW ;
SCHIFF, I ;
ROSNER, B ;
GREENBERG, L ;
RAVNIKAR, V ;
SACKS, FM .
NEW ENGLAND JOURNAL OF MEDICINE, 1991, 325 (17) :1196-1204
[7]   ESTROGEN MODULATES RESPONSES OF ATHEROSCLEROTIC CORONARY-ARTERIES [J].
WILLIAMS, JK ;
ADAMS, MR ;
KLOPFENSTEIN, HS .
CIRCULATION, 1990, 81 (05) :1680-1687
[8]   Abnormal vascular function and hypertension in mice deficient in estrogen receptor β [J].
Zhu, Y ;
Bian, Z ;
Lu, P ;
Karas, RH ;
Bao, L ;
Cox, D ;
Hodgin, J ;
Shaul, PW ;
Thorén, P ;
Smithies, O ;
Gustafsson, JÅ ;
Mendelsohn, ME .
SCIENCE, 2002, 295 (5554) :505-508