Corrected and Uncorrected Near and Distance Vision with ReSTOR® Compared to Monofocal Intraocular Lens Implantation after Cataract Surgery: A Pooled Analysis

Background/Aim: To evaluate distance and near vision-related benefit after implantation of ReSTOR (R) multifocal intraocular lenses (IOLs) following cataract surgery. Methods: Two prospective open-labeled nonrandomized studies were pooled. Patients' perception of benefit was assessed with the TyPE, administered at baseline and after each eye surgery. Results: A total of 499 patients received ReSTOR IOLs, and 173 received monofocal IOLs. The distance vision of monofocal and ReSTOR patients improved equally with and without glasses. A greater improvement in near vision without glasses was reported by ReSTOR-implanted patients as early as after the 1st eye surgery (p < 0.0001). More ReSTOR patients than monofocal patients reported independence from glasses after the 1st eye surgery (64 vs. 52%; p = 0.0002). This difference had increased after the 2nd eye surgery (85 vs. 51%; p < 0.0001). Conclusions: The improvement in near vision without glasses was significantly more evident in ReSTOR patients, allowing the majority of them to be free of glasses. Copyright (C) 2008 S. Karger AG, Basel