Development of an Electrochemical Quartz Crystal Microbalance-Based Immunosensor for C-reactive protein determination

被引：7

作者：

Gao, Kai ^{[1
]}

Cui, Song ^{[1
]}

Liu, Sibo ^{[1
]}

机构：

[1] Dalian Municipal Cent Hosp, Dept Crit Care Med, Dalian 116001, Liaolin Provinc, Peoples R China

来源：

INTERNATIONAL JOURNAL OF ELECTROCHEMICAL SCIENCE | 2018年 / 13卷 / 01期

关键词：

Electrochemical quartz crystal microbalance; Immunosensor; Inflammation Marker; C-reactive protein; Limit of detection; LABEL-FREE DETECTION; MODIFIED GOLD ELECTRODES; EPIDEMIOLOGIC APPLICATIONS; ANTIBODY; BIOSENSOR; INFLAMMATION; ASSOCIATION; MARKERS; SENSOR; FILMS;

D O I：

10.20964/2018.01.49

中图分类号：

O646 [电化学、电解、磁化学];

学科分类号：

081704 ;

摘要：

In terms of outcome prediction in patients with inflammation, albumin and C-reactive protein (CRP) at serum levels have been considered to constitute a practical and reliable scoring system. In the present work, highly sensitive detection of C-reactive protein (hs-CRP) was achieved via a new strategy using a quartz crystal microbalance (QCM) immunosensor. A linear relationship was found between the QCM response and CRP concentration (0.04 - 30 mu g/mL), with a low limit of detection (LOD) maintained via an amplification process.

引用

页码：812 / 821

页数：10

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