Development of an ultrahigh-resolution Si-PM-based dual-head GAGG coincidence imaging system

被引:11
作者
Yamamoto, Seiichi [1 ]
Watabe, Hiroshi [2 ]
Kanai, Yasukazu [2 ]
Kato, Katsuhiko
Hatazawa, Jun [2 ,3 ]
机构
[1] Nagoya Univ, Grad Sch Med, Dept Radiol & Med Lab Sci, Higashi Ku, Nagoya, Aichi 4618673, Japan
[2] Osaka Univ, Grad Sch Med, Dept Mol Imaging Med, Osaka, Japan
[3] Osaka Univ, Grad Sch Med, Dept Nucl Med & Tracer Kinet, Osaka, Japan
关键词
Si-PM; Coincidence; Imaging; Ultra high resolution; GAGG; PET; DETECTOR;
D O I
10.1016/j.nima.2012.11.098
中图分类号
TH7 [仪器、仪表];
学科分类号
0804 ; 080401 ; 081102 ;
摘要
A silicon photomultiplier (Si-PM) is a promising photodetector for high resolution PET systems due to its small channel size and high gain. Using Si-PMs, it will be possible to develop a high resolution imaging systems. For this purpose, we developed a small field-of-view (FOV) ultrahigh-resolution Si-PM-based dual-head coincidence imaging system for small animals and plant research. A new scintillator, Ce doped Gd3Al12Ga3O12 (GAGG), was selected because of its high light output and its emission wavelength matched with the Si-PM arrays and contained no radioactivity. Each coincidence imaging block detector consists of 0.5 x 0.5 x 5 mm(3) GAGG pixels combined with a 0.1-mm thick reflector to form a 20 x 17 matrix that was optically coupled to a Si-PM array (Hamamatsu MPPC S11064-050P) with a 1.5-mm thick light guide. The GAGG block size was 12.0 x 10.2 mm(2). Two GAGG block detectors were positioned face to face and set on a flexible arm based detector stand. All 0.5 mm GAGG pixels in the block detectors were clearly resolved in the 2-dimensional position histogram. The energy resolution was 14.4% FWHM for the Cs-137 gamma ray. The spatial resolution was 0.7 mm FWHM measured using a 0.25 mm diameter Na-22 point source. Small animal and plant images were successfully obtained. We conclude that our developed ultrahigh-resolution Si-PM-based dual-head coincidence imaging system is promising for small animal and plant imaging research. (C) 2012 Elsevier B.V. All rights reserved.
引用
收藏
页码:183 / 189
页数:7
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