Organocatalytic three-component cascade reaction for the synthesis of spiro[indeno[1,2-b]furan]-triones

被引:13
|
作者
Ahadi, Somayeh [1 ]
Abaszadeh, Maryam [1 ]
Bazgir, Ayoob [1 ]
机构
[1] Shahid Beheshti Univ, Dept Chem, GC, Tehran, Iran
基金
美国国家科学基金会;
关键词
3-Bromo-4-hydroxycoumarin; Spiro[indeno[1,2-b]furan]-triones; Organocatalysis; STEREOSELECTIVE-SYNTHESIS; DIHYDROFURANS; ALDEHYDES; DBU; COMBINATORIAL; CYCLIZATION; PARALLEL; MICHAEL; FACILE; YLIDES;
D O I
10.1007/s11030-012-9363-4
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
New methods for the synthesis of spiro compounds containing dihydrofuran and coumarin moieties from 3-bromo-4-hydroxycoumarins as cyclic alpha-halo compound based on a pyridinium-ylide-assisted three-component tandem reaction is investigated. To the best of our knowledge, employing cyclic alpha-halo compounds for the synthesis of dihydrofuran-fused coumarin via a pyridinium ylide has not been reported yet.
引用
收藏
页码:299 / 306
页数:8
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