Molecular Imaging Biomarkers for Oncology Clinical Trials

被引:55
作者
Mankoff, David A. [1 ]
Pryma, Daniel A. [1 ]
Clark, Amy S. [2 ]
机构
[1] Univ Penn, Perelman Sch Med, Philadelphia, PA 19104 USA
[2] Univ Penn, Perelman Sch Med, Abramson Canc Ctr, Philadelphia, PA 19104 USA
关键词
cancer biomarkers; clinical trials; cancer therapy; BREAST-CANCER; FDG-PET; TRASTUZUMAB; CRITERIA;
D O I
10.2967/jnumed.113.126128
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
Biomarkers can be used to characterize disease status or predict disease behavior. Cancer biomarkers have typically relied on assays of blood or tissue; however, molecular imaging has a promising and complementary role as a cancer biomarker. This "Focus on Molecular Imaging" article reviews the current role of biomarkers to direct cancer clinical trials and clinical practice, along with current and future cancer biomarker applications of molecular imaging.
引用
收藏
页码:525 / 528
页数:4
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