Review: Biotechnology of mycotoxins detoxification using microorganisms and enzymes

被引：99

作者：

Ben Taheur, Fadia ^{[1
]}

Kouidhi, Bochra ^{[2
]}

Al Qurashi, Yasir Mohammed A. ^{[2
]}

Ben Salah-Abbes, Jalila ^{[3
]}

Chaieb, Kamel ^{[1
]}

机构：

[1] Monastir Univ, Fac Pharm, Lab Anal Treatment & Valorizat Environm Pollutant, Monastir, Tunisia

[2] Taibah Univ, Coll Appl Med Sci, Med Lab Dept, Yanbu El Bahr, Saudi Arabia

[3] Monastir Univ, Higher Inst Biotechnol, Lab Genet Biodivers & Bioressources Valorizat, Monastir, Tunisia

来源：

TOXICON | 2019年 / 160卷

关键词：

Mycotoxins; Bacteria; Fungi; Yeast; Enzymes; Binding; Detoxification; LACTIC-ACID BACTERIA; LACTOBACILLUS-PLANTARUM MON03; AFLATOXIN DEGRADATION ENZYME; LC-MS/MS METHOD; OCHRATOXIN-A; IN-VITRO; SACCHAROMYCES-CEREVISIAE; FUSARIUM-MYCOTOXINS; RISK-ASSESSMENT; OXIDATIVE STRESS;

D O I：

10.1016/j.toxicon.2019.02.001

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Mycotoxins are secondary metabolites produced by various toxigenic fungi belonging to the genera Aspergillus, Fusarium and Penicillium. They have mutagenic, teratogenic, carcinogenic, immunosuppressive and endocrine disrupting effects on both humans and animals. The ubiquitous occurrence and heat stability of these mycotoxins during food and feed processing pose serious health problems in human and animals. Therefore successful biotechnological detoxification tools are in great demand. Recently, the use of bacteria, yeast, moulds and enzymes to mitigate/bind or biodegrade various mycotoxins is a novel strategy used for mycotoxins removal. In this review, recent development in biological control of mycotoxins removal and detoxification will be discussed.

引用

页码：12 / 22

页数：11

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