Reelin glycoprotein in autism and schizophrenia

被引：43

作者：

Fatemi, SH ^{[1
]}

机构：

[1] Univ Minnesota, Sch Med, Dept Psychiat, Minneapolis, MN 55455 USA

来源：

GABA IN AUTISM AND RELATED DISORDERS | 2005年 / 71卷

关键词：

D O I：

10.1016/S0074-7742(05)71008-4

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Reelin glycoprotein is a serine protease with important roles in embryogenesis and in adult life. Reelin mutations or deficiency of the protein product could cause abnormal cortical development and/or Reelin-induced signal transduction impairment in brain. Reelin abnormalities in several neuropsychiatric disorders, such as autism and schizophrenia, may provide mechanistic explanations for etiologies of these disorders.

引用

页码：179 / 187

页数：9

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