Pd-Catalyzed C-H activation/oxidative cyclization of acetanilide with norbornene: concise access to functionalized indolines

被引：51

作者：

Gao, Yang ^{[1
]}

Huang, Yubing ^{[1
]}

Wu, Wanqing ^{[1
]}

Huang, Kefan ^{[1
]}

Jiang, Huanfeng ^{[1
]}

机构：

[1] S China Univ Technol, Sch Chem & Chem Engn, Guangzhou 510640, Guangdong, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2014年 / 50卷 / 61期

基金：

中国国家自然科学基金;

关键词：

BOND FUNCTIONALIZATION; INDOLES; ALKYLATION; ARYLATION; OLEFINS; CYCLOADDITION; SUBSTITUTION; ANNULATION; VINYLATION; PRODUCTS;

D O I：

10.1039/c4cc03062a

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

An efficient Pd-catalyzed oxidative cyclization reaction for the synthesis of functionalized indolines by direct C-H activation of acetanilide has been developed. The norbornylpalladium species formed via direct ortho C-H activation of acetanilides is supposed to be a key intermediate in this transformation.

引用

页码：8370 / 8373

页数：4

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