Tumor markers in endometriosis

被引：40
作者：
Abrao, MS [1 ]
Podgaec, S [1 ]
Pinotti, JA [1 ]
de Oliveira, RM [1 ]
机构：
[1] Univ Sao Paulo, Sch Med, Dept Obstet & Gynecol, Sao Paulo, Brazil
来源：
INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS | 1999年 / 66卷 / 01期
关键词：
endometriosis; biological tumor markers; CA; 125; 15-3; 19-9; CEA; alpha-fetoprotein; beta-2-microglobulin;
D O I：
10.1016/S0020-7292(99)00046-6
中图分类号：
R71 [妇产科学];
学科分类号：
100211 ;
摘要：
Objectives: The objective of the present study was to determine the concentrations of CA 125, CA 15-3, CA 19-9, carcioembryogenic antigen (CEA), alpha-fetoprotein (AFP) and beta-2 microglobulin (B2MG) in patients with pelvic endometriosis. Method: Fifty women were divided into two groups: group A (control) had no endometriosis or other diseases, and group B consisted of 35 women with pelvic endometriosis. All women were submitted to serum determination of CA 125, CA 15-3, CA 19-9, CEA, AFP and B2MG. Samples were collected during the menstrual cycle and 1 week later. Results: Mean CA 125 concentrations were altered in patients with endometriosis, but all 50 patients studied presented normal CEA, AFP and B2MG concentrations. Small variations detected in CA 19-9 and CA 15-3 had no statistical significance. Conclusion: CA 125 is the only important marker in the diagnosis of stages III/IV of endometriosis, especially when blood samples for its determination are obtained during the first 3 days of the menstrual cycle. (C) 1999 The International Federation of Gynecology and Obstetrics.
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页码：19 / 22
页数：4
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