Benign pleomorphic astrocytoma in the hypothalamus - Case report

被引:10
作者
Abe, T
Inoue, R
Isono, M
Ishii, K
Fujiki, M
Kamida, T
Kobayashi, H
Kashima, K
Kusakabe, T
Nakazato, Y
机构
[1] Oita Univ, Dept Neurosurg, Fac Med, Oita 8795593, Japan
[2] Oita Univ, Dept Pathol, Fac Med, Oita 8795593, Japan
[3] Nannkai Hosp, Dept Neurosurg, Oita, Japan
[4] Gunma Univ, Sch Med, Dept Pathol, Maebashi, Gumma 371, Japan
关键词
astrocytoma; pleomorphism; pleomorphic xanthoastrocytoma;
D O I
10.2176/nmc.46.101
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
A 41-year-old woman presented with an unusual case of benign astrocytoma with marked pleomorphism manifesting as consciousness disturbance due to intraventricular hemorrhage. Magnetic resonance imaging revealed a well-enhanced hypothalamic mass protruding into the third ventricle. Despite partial resection of the tumor without additional therapy, there have been no signs of tumor regrowth for 6 years. The histological findings revealed solid proliferation of tumor cells with marked pleomorphism, contrary to the benign clinical course. However, no mitosis, necrosis, or endothelial proliferation were found and the MIB-1 index was less than 0.5%. Immunohistochemical staining indicated the glial origin of the tumor. The tumor was similar to pleomorphic xanthoastrocytoma, but the histological findings were not exactly identical, indicating a new histological entity.
引用
收藏
页码:101 / 103
页数:3
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