Allicin from garlic strongly inhibits cysteine proteinases and cytopathic effects of Entamoeba histolytica

被引:122
作者
Ankri, S [1 ]
Miron, T [1 ]
Rabinkov, A [1 ]
Wilchek, M [1 ]
Mirelman, D [1 ]
机构
[1] WEIZMANN INST SCI,DEPT MEMBRANE RES & BIOPHYS,IL-76100 REHOVOT,ISRAEL
关键词
D O I
10.1128/AAC.41.10.2286
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
The ability of Entamoeba histolytica trophozoites to destroy monolayers of baby hamster kidney cells is inhibited by allicin, one of the active principles of garlic. Cysteine proteinases, an important contributor to amebic virulence, as well as alcohol dehydrogenase, are strongly inhibited by allicin.
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页码:2286 / 2288
页数:3
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